Chromosomal Damage, Chromosome Instability, and Polymorphisms in and as Biomarkers of Effect and Susceptibility in Farmers Exposed to Pesticides.

In the department of Boyacá, Colombia, agriculture stands as one of the primary economic activities. However, the escalating utilization of pesticides within this sector has sparked concern regarding its potential correlation with elevated risks of genotoxicity, chromosomal alterations, and carcinogenesis. Furthermore, pesticides have been associated with a broad spectrum of genetic polymorphisms that impact pivotal genes involved in pesticide metabolism and DNA repair, among other processes.

[Cardiovascular risk markers in schoolchildren from five provinces of eastern Colombia].

Introduction: Cardiovascular disease is a public health problem globally; it represents the second cause of mortality in Colombia. This highlights the importance of identifying risk markers from the time of childhood, in order to diminish mortality rates proactively.

Objectives: The lipid profile, homocysteine and C reactive protein plasma concentrations were determined in order to identify relationships between these markers and age, sex and school type.

[Genetic polymorphism of the E apolipoprotein in school age children: comparison with levels of plasma lipids and apolipoproteins].

Introduction: Research in laboratories around the world has documented the contribution of the E apolipoprotein alleles to structural variations of lipids and apolipoproteins.

Objective: The gene frequencies of the E apolipoprotein alleles were compared with the lipid and apolipoprotein levels in school age children.

Materials And Methods: Six hundred and ninety one 5 to 15 years old school age children from the Colombian departments of Cundinamarca, Boyacá, Meta, Santander and Norte de Santander, were evaluated.

[Leptin levels in school age children associated with anthropometric measurements and lipid profiles].

Introduction: Leptins are proteins that regulate body weight. Their concentrations are modified depending on several factors including metabolic status, diabetes mellitus type 2 and cardiovascular diseases.

Objective: The leptin concentrations were measured in Colombian children and related to age, sex, body mass index, triceps skinfold and lipid profile.

[Lipid and apoprotein A-I and B-100 levels in school children school from five central-eastern provinces of Colombia].

Introduction: Lipid and apolipoprotein are known to vary in children.These variations can be associated to physiologic changes or the environment; this last one probably induces future alterations in the lipids.

Objective: The levels of total cholesterol, LDL-cholesterol, HDL-cholesterol, and apoproteins A-I and B-100 were compared in school children from five provinces of middle-eastern Colombia.

[Effects of vegetal oil supplementation on the lipid profile of Wistar rats ].

Background: Dietary tocopherols, tocotrienols and saturated, mono and polyunsaturated fatty acids have been reported to have an effect on blood lipid profiles. In Colombia, vegetable oils (palm, soy, corn, sunflower, and canola) are a common dietary constituent and consumed in high quantities.

Objective: In the current study, the effects of vegetable oil consumption was examined by measuring blood concentrations of triglycerides (TG), total cholesterol (TC) and HDL cholesterol (HDL-C) in male Wistar rats.

[Stability and effect of ingestion on the levels of folate in plasma].

The physiological demand of folates increases during adolescence, pregnancy and lactation due to the rapid growth and anabolic activity during these stages of life. The periconceptional deficiency of folates is a risk for the presence of neural tube defects. We studied the stability of folates concentration in plasma and the effect of ingestion of a breakfast rich in folates on the postprandial levels of this micronutrient, up to two hours after food intake.