Comparative genomic hybridization in primary sinonasal adenocarcinomas.

Background: Little is known about the genetic alterations that occur in sinonasal adenocarcinomas. The goal of the current study was to detect recurrent chromosomal gains and losses in a series of 21 primary sinonasal adenocarcinomas using comparative genomic hybridization (CGH).

Methods: The authors examined ethmoid sinus adenocarcinoma samples from 21 patients.