Publications by authors named "Cervantes J"

A 69-year-old man underwent liver transplantation with a deceased donor for cirrhosis secondary to steatohepatitis. The arterial anastomosis was performed between the celiac trunk of the donor and the hepatic artery of the recipient. In the second postoperative month, he developed abdominal pain and abnormal liver function tests.

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Importance: Recent evolutions in clinical care and remote monitoring suggest that some acute illnesses no longer require intravenous therapy and inpatient hospitalization.

Objective: To describe outcomes of patients receiving care in a new, outpatient, virtual, home-based acute care model called Safer@Home.

Design, Setting, And Participants: This retrospective cohort analysis, conducted from September 1, 2022, through August 31, 2023, included 2466 patients treated at a safety net hospital in Los Angeles County for 10 core illnesses and 24 other acute illnesses for which patients are commonly hospitalized.

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Objective: Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related mortality globally. In our region, there is a scarcity of studies addressing its epidemiology and treatment. The aim was to characterize a cohort of HCC patients in a high-complexity public center in Argentina over a span of 10 years.

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During nuclear fuel reprocessing, radioiodine, can be released. The speciation of iodine drives its volatility, and partitioning processes are highly variable because they depend on facility operating conditions. Starting from iodine behavior in the fuel and progressing to its behavior in the environment, this review article describes the current understanding of iodine partitioning during aqueous fuel reprocessing.

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This report presents the case of a 20-year-old man who sustained a severe liver injury from a closerange shotgun blast. A prompt medical intervention, including damage control exploratory laparotomy and surgical debridement, was undertaken due to the extent of liver damage. Despite challenges such as a nondirected biliary fistula and extensive liver parenchymal injury, comprehensive surgical management led to successful treatment.

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Article Synopsis
  • SLITs are proteins that act as ligands for ROBO receptors, which are important for cell signaling.
  • Research indicates that ROBO1 helps mammary cells differentiate and produce milk by blocking Notch signaling.
  • In experiments, knockout mice lacking SLIT2 and SLIT3 showed better development of milk-producing cells and higher milk production, suggesting that SLITs inhibit this process by interfering with ROBO1.
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Infection with can spread and cause central nervous system involvement, known as neuroborreliosis. Microglia phagocytose bacteria, mediate inflammation, and elicit an immune response toward the spirochete. Like other tissue macrophages, microglia can polarize into two different modulatory phenotypes, M1 and M2.

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Xylazine, commonly referred to as "Tranq," is an alpha-2-adrenergic receptor agonist that is FDA-approved only as a sedative and tranquilizer for veterinary use. However, its use as an adulterant in various illicit drugs, including fentanyl, has been on the rise, leading to its street name, "Tranq-Dope." Intravenous injection use of xylazine produces distinctive skin ulceration with accompanying necrosis, which can be considered virtually pathognomonic.

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Background: The World Database for Pediatric and Congenital Heart Surgery (WDPCHS), sponsored by the World Society for Pediatric and Congenital Heart Surgery (WSPCHS), provides complex congenital heart surgery outcomes analyses for member programs. This report represents the seven-year descriptive analysis of outcomes from active members of the WDPCHS.

Methods: Individual institutions submit data based on the specific procedure via a password protected platform.

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Previously, many studies have reported changes in the gut microbiota of patients with colorectal cancer (CRC). While CRC is a well-described disease, the relationship between its development and features of the intestinal microbiome is still being understood. Evidence linking enrichment in colorectal tumor tissue has prompted the elucidation of various molecular mechanisms and tumor-promoting attributes.

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Article Synopsis
  • Hepatocellular carcinoma (HCC) is the most prevalent type of primary liver cancer and is a leading cause of cancer deaths globally, with treatment options varying based on whether the patient has cirrhosis.
  • A retrospective study at Hospital El Cruce over seven years analyzed 44 patients who underwent hepatic resection, evaluating their recovery outcomes, recurrence rates, and overall survival.
  • Findings indicated that 59% of patients experienced disease recurrence, with factors like tumor size and AFP levels influencing this; surprisingly, cirrhotic patients showed better survival rates than non-cirrhotic ones, highlighting the need for ongoing monitoring for recurrence.
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The state of emotional, physical, and mental exhaustion caused by excessive and prolonged stress, known as Burnout Syndrome (BS), is not only affecting the medical workforce but medical students in training. Gender, race, ethnicity, and potentially other variables can serve as significant risk factors contributing to BS among medical students. Despite the importance of understanding these disparities, very few studies in the U.

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Article Synopsis
  • - The study examined how various factors like sex, vaccine type, body fat percentage, and stress affect immune responses (measured by Ig-G anti-RBD) to COVID-19 in 108 young participants, mostly females with an average age of 21.4.
  • - Results showed that body fat percentage impacts immune response differently in males and females: increased body fat decreased Ig-G levels in males, while it increased levels in females, regardless of the vaccine used.
  • - These findings suggest the importance of considering sex and body composition in understanding vaccine efficacy and could guide educational and health policies to reduce health disparities related to COVID-19.
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Hip dysplasia is a pathomorphologic deformity that leads to decreased acetabular coverage and hip instability. Many different radiographic measurements have been explored to characterize hip dysplasia, including the lateral center-edge angle, femoral-epiphyseal acetabular roof index, and Tönnis angle. Magnetic resonance imaging offers 3-dimensional characterization of the hip pathomorphology that may be more detailed than 2-dimensional radiographs, as well as a modality that is free of radiation.

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Sign language is a complete language with its own grammatical rules, akin to any spoken language used worldwide. It comprises two main components: static words and ideograms. Ideograms involve hand movements and contact with various parts of the body to convey meaning.

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Acetaminophen is a commonly used analgesic and antipyretic drug, which has experienced an increase in its consumption in recent years in our environment. There has also been an increase in the number of accidental and intentional overdoses that were treated by the health system. Its toxicity is dose-dependent and can cause fulminant liver failure, becoming one of the main reasons for liver transplantation in English-speaking countries.

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Effect of an aperture in atomic gravimetry.

J Opt Soc Am A Opt Image Sci Vis

May 2024

There is a continuous interest in shrinking the dimensions of portable atomic gravimeters. This inevitably ends up truncating the Gaussian wings of the excitation laser beams whose effect has not been properly quantified yet. The diffraction pattern created from this aperture creates ripples in the wavefront in both the phase and the intensity.

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A series of amphiphilic block copolymer (BCP) micelles based on poly(dimethylsiloxane) (PDMS) and poly(ethylene glycol) (PEG) were synthesized by a one-step reaction in the presence of tris(pentafluorophenyl)borane (BCF) as a catalyst. The structural composition of PDMS--PEG (PR11) and PEG--PDMS--PEG (PR12) was corroborated by FTIR, Si NMR, and TGA. The BCPs were assembled in an aqueous solution, obtaining micelles between 57 and 87 nm in size.

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Generative AI (GenAI) is a disruptive technology likely to generate a major impact on faculty and learners in medical education. This work aims to measure the perception of GenAI among medical educators and to gain insights into its major advantages and concerns in medical education. A survey invitation was distributed to medical education faculty of colleges of allopathic and osteopathic medicine within a single university during the fall of 2023.

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Protein retention expansion microscopy (ExM) retains genetically encoded fluorescent proteins or antibody-conjugated fluorescent probes in fixed tissue and isotropically expands the tissue through a swellable polymer network to allow nanoscale (<70 nm) resolution on diffraction-limited confocal microscopes. Despite numerous advantages ExM brings to biological studies, the full protocol is time-consuming and can take multiple days to complete. Here, we adapted the ExM protocol to the vibratome-sectioned brain tissue of tadpoles and implemented a microwave-assisted protocol to reduce the workflow from days to hours.

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Article Synopsis
  • - Diabetes significantly raises the risk of heart and kidney diseases, particularly highlighting that those with kidney disease face even higher cardiovascular risks.
  • - The study found that higher levels of apolipoprotein C3 (APOC3) in patients with type 2 diabetes predict worse kidney function, suggesting it plays a role in diabetic kidney disease and atherosclerosis.
  • - By silencing APOC3 in diabetic mice, researchers observed reduced kidney damage and atherosclerosis, indicating that targeting APOC3 could be a promising strategy for treating these diabetes-related complications.
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The COVID-19 pandemic has underscored the urgent need for microbiology literacy in society. Microbiology knowledge, and its dissemination, can help inform and increase the objectivity of important decisions, such as treatment or vaccination. A microbiology learning experience titled "What you can't see can hurt you" was delivered as part of a larger outreach event where children were exposed to various aspects of medicine and health care fields.

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Layla is a 6.7-year-old girl diagnosed with attention-deficit/hyperactivity disorder (ADHD)-predominantly hyperactive/impulsive type-delayed adaptive skills, enuresis, unspecified malnutrition, and feeding difficulties. She presented to developmental-behavioral pediatrics (DBP) in January 2022 due to caregiver concerns for autism spectrum disorder (ASD).

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The precise segmentation of white blood cells (WBCs) within blood smear images is a significant challenge with implications for both medical research and image processing. Of particular importance is the often neglected task of accurately segmenting WBC nuclei, an aspect that currently lacks dedicated methodologies. This paper introduces a straightforward and efficient method designed to fill this critical gap, providing an effective solution for the efficient segmentation of WBC nuclei.

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