Brain-derived neurotrophic factor: Its role in energy balance and cancer cachexia.

Brain-derived neurotrophic factor (BDNF) plays an important role in the development of the central and peripheral nervous system during embryogenesis. In the mature central nervous system, BDNF is required for the maintenance and enhancement of synaptic transmissions and the survival of neurons. Particularly, it is involved in the modulation of neurocircuits that control energy balance through food intake, energy expenditure, and locomotion.

Role of Reduced Bdnf Expression in Novel Apc Mutant Allele-induced Intestinal and Colonic Tumorigenesis in Mice.

Background/aim: Brain-derived neurotrophic factor (BDNF) is a growth factor of the neurotrophin family. Recent studies indicate that its expression is regulated by Wnt/β-catenin signaling. In this study, we aimed to examine the effects of reduced Bdnf levels in an Apc mutant intestinal/colonic tumor mouse model.

Clinical trials and promising preclinical applications of CRISPR/Cas gene editing.

Treatment of genetic disorders by genomic manipulation has been the unreachable goal of researchers for many decades. Although our understanding of the genetic basis of genetic diseases has advanced tremendously in the last few decades, the tools developed for genomic editing were not efficient and practical for their use in the clinical setting until now. The recent advancements in the research of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR-associated protein (Cas) systems offered an easy and efficient way to edit the genome and accelerated the research on their potential use in the treatment of genetic disorders.

Description of New Miridae and Tingidae Species (Hemiptera: Heteroptera) and New Records from Southern Turkey.

In this study, Fulvius anatolicus Çerçi Gorczyca sp. n., Orthotylus (Pinocapsus) kmenti Çerçi Koçak sp.

Review of Reuteria Puton, 1875 (Heteroptera: Miridae) species present in Lodos Entomological Museum, Turkey (LEMT).

The species belonging to Reuteria Puton 1875 present in Lodos Entomological Museum, Turkey (LEMT) are reviewed. Up to now, only Reuteria marqueti Puton 1875 and R. winkelmanni Günther Strauss 2018 had been recorded from Turkey.

sp. nov. (Heteroptera: Miridae) from Turkey.

A new species of the genus Isometopus, Isometopus anlasi sp. nov. (Heteroptera: Miridae) is described based on both male and female specimens.