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Publications by authors named "Cenyu Xiao"

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Study on the Effect of the Vaginal Administration of Conjugated Estrogens Cream Combined with Progesterone on the Endometrium of Rats and Its Mechanism of Action.
Panpan Li Cenyu Xiao Zhiyuan Lv Haiyang Cui Xiaoli Gao

Biomedicines

September 2024

Article Synopsis
  • The study examined how vaginally-administered conjugated estrogen cream with progesterone affects the endometrium in a hypoestrogenic rat model, mimicking perimenopause.*
  • After 12 days of treatment, results showed that estrogen significantly increased uterine weight and endometrial thickness while also affecting specific protein expressions.*
  • The addition of progesterone reversed these estrogen effects in a dose-dependent manner, suggesting it can help prevent endometrial hyperplasia caused by estrogen alone.*
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