Preparation and Antibacterial Properties of Poly (l-Lactic Acid)-Oriented Microporous Materials.

In this manuscript, an efficient self-reinforcing technology-solid hot drawing (SHD) technology-was combined with green processing supercritical carbon dioxide (SC-CO) foaming technology to promote poly (l-lactic acid) (PLLA) to form an oriented micropore structure. In addition, Polydimethylsiloxane (PDMS), with a high affinity of CO and biological safety, was introduced to enhance the nucleation effect in SC-CO foaming and co-regulate the uniformity of oriented micropores' structure. The results showed that orientation induced PLLA crystallization, so the tensile strength was improved; the maximum tensile strength of the oriented micropores' PLLA reached 151.

Preparation and properties of polydimethylsiloxane-regulated oriented microporous poly (-lactic acid) biomimetic bone repair materials.

Despite the exceptional biocompatibility and degradability of Poly (-lactic acid) (PLLA), its brittleness, low melting strength, and poor bone induction makes it challenging to utilize for bone repair. This study used a simple, efficient solid hot drawing (SHD) method to produce high-strength PLLA, using supercritical CO (SC-CO) foaming technology to give PLLA a bionic microporous structure to enhance its toughness, while precisely controlling micropore homogeneity and improving the melt strength by using Polydimethylsiloxane (PDMS). This PDMS-regulated oriented microporous structure resembled that of natural bone, displaying a maximum tensile strength of 165.