Socioeconomic status has direct impact on asthma control: Turkish adult asthma registry.

Background: Asthma is one of the most common causes of chronic respiratory disease, and countries with low socioeconomic status have both a high prevalence of asthma and asthma-related death.

Objective: In this study, we aimed to determine socioeconomic levels of asthmatic patients according to a national database and investigate the effects of social markers on disease control in our region.

Methods: This is an analysis of data from 2053 adult asthma patients from a multicentre chart study in Turkey.

Trends in prescribing montelukast in patients with asthma in real-life: Results from the Turkish adult asthma registry.

Montelukast, a leukotriene receptor antagonist (LTRA) approved for the treatment of asthma and allergic rhinitis, is widely used, though real-world data on its application in asthma management remain limited. This registry-based study evaluated the use of montelukast in adult asthma patients, examining demographic and disease characteristics, asthma control status, asthma phenotypes, presence of atopy, and treatment regimens. Among 2053 patients analyzed, 61.

Narrow escape with imperfect reactions.

The imperfect narrow escape problem considers the mean first passage time (MFPT) of a Brownian particle through one of several small, partially reactive traps on an otherwise reflecting boundary within a confining domain. Mathematically, this problem is equivalent to Poisson's equation with mixed Neumann-Robin boundary conditions. Here, we obtain this MFPT in general three-dimensional domains by using strong localized perturbation theory in the small trap limit.

Factors influencing the prescription of add-on long-acting muscarinic antagonists in real-world asthma management: Insights from a national registry.

Current guidelines recommend adding long-acting muscarinic antagonists (LAMAs) in patients with uncontrolled asthma, despite the use of moderate to high doses of inhaled steroid-long-acting beta agonists (ICS/LABA). This study aims to analyze the factors related to the prescription of add-on LAMA in clinical practice for asthma patients, shedding light on physicians' preferences. This study included adult asthma patients on add-on LAMA and ICS/LABA monitored for at least one year in a national registry comprising 2053 asthmatics.

Efficacy of Nematode Against Lesser Mealworm () Populations from Poultry Farms in Türkiye.

In the veterinary field, particularly in the poultry farming sector, (Panzer, 1797) (Coleoptera: Tenebrionidae) is a significant pest that causes economic losses and acts as a vector for various pathogens. This study is the first to evaluate the efficacy of the entomopathogenic nematode Filipjev, 1934 against both the larval (fifth instar) and imago (adult) of from various Turkish populations. The insects were collected from six poultry farms in the provinces of Balikesir, Bolu, Canakkale, Manisa, and Izmir in Türkiye, bred, and then tested at concentrations ranging from 25 to 200 infective juveniles (IJs) per milliliter.

Infections and treatment modalities in pediatric victims of the Kahramanmaraş/Türkiye earthquake.

Background: Data on infections in children are scarce in the context of earthquakes. Here, we describe our clinical experiences regarding infections in pediatric victims after the earthquakes in Kahramanmaraş/Türkiye.

Methods: Trauma patients after the Kahramanmaraş earthquakes, aged under 18 years and admitted to our hospital, were evaluated retrospectively.

Early oral colonization of streptococcus mutans and lactobacilli species in infants: Investigating the relationship with maternal and environmental factors, from birth through the sixth month.

Objective: To assess the presence of () and species () of newborn-mother pairs using the real time polymerase chain reaction (qRT-PCR).

Method: Subjects were selected from the patients followed in the Neonatology Clinic of Akdeniz University's Faculty of Medicine between the years 2017-2018. First samples collected within 48 hours after birth, and second samples were at six months.

Is the high dose extended infusion of meropenem useful in the treatment of highly resistant gram-negative bacteria in children?

Objectives: Multidrug resistant infections present a treatment challenge for clinicians. These infections have been associated with increased morbidity and mortality. Recently, there has been increasing discussion in the literature that high dose extended infusion of meropenem may be helpful.

Plasma Extracellular Vesicles Derived from Pediatric COVID-19 Patients Modulate Monocyte and T Cell Immune Responses Based on Disease Severity.

Background: The COVID-19 pandemic has caused significant morbidity and mortality globally. The role of plasma-derived extracellular vesicles (EVs) in pediatric COVID-19 patients remains unclear.

Methods: We isolated EVs from healthy controls (n = 13) and pediatric COVID-19 patients (n = 104) with varying severity during acute and convalescent phases using serial ultracentrifugation.

The opinions and experiences of nursing students, nurses, and patients regarding clinical practices: A mixed-methods study.

The aim of this mixed-methods study was to examine the experiences of nursing students (NSs), nurses, and patients regarding the clinical practices of NSs and to determine NSs' stress levels regarding clinical practices. The quantitative part of the study was completed with 240 NSs, and the "Perceived Stress Scale for Nursing Students" was used. In the qualitative part, the focus group interviews were held with 24 NSs, and the individual interviews were conducted with 15 patients and 20 nurses.

Pandemic of the century: COVID-19 in inflammatory rheumatic diseases of a national cohort with 3,532 patients.

Objectives: This study aimed to assess the clinical outcomes and risk factors for severe coronavirus disease 2019 (COVID-19) in patients with inflammatory rheumatic disease (IRD) of a national cohort.

Patients And Methods: The multicenter cross-sectional study was carried out between July 15, 2020, and February 28, 2021. Data collection was provided from a national network database system, and 3,532 IRD patients (2,359 males, 1,173 females; mean age: 48.

Larvicidal and repellent effects of essential oils on the brown dog tick (Rhipicephalus sanguineus Sensu lato) with description of new larval repellent activity test method.

The aim of this research was to investigate the larvicidal and repellent effects of essential oils (EOs) obtained from two Lamiaceae plant species, Origanum minutiflorum O. Schwarz & P.H.

Spectrophotometric analysis of the effectiveness of different dentin tubule occlusion techniques in preventing discoloration caused by photosensitizers used in photodynamic therapy.

Aim: The efficacy of Copal Varnish (CV), dentin bonding agent (DBA), Nd:YAG laser and Er:YAG laser, which occludes dentin tubules by different mechanisms, was investigated in order to prevent unwanted coloration caused by methylene blue (MB) and phthalocyanine used in photodynamic therapy (PDT).

Materials And Methods: 165 upper incisors included in the study. Root canals were prepared up to 30/0.

Comparative evaluation of the clinical success of 3D-printed space maintainers and band-loop space maintainers.

Background: Exploring the integration of 3D-printing technology in space maintainer (SM) manufacturing could offer innovative solutions and insights for enhancing SMs.

Aim: To compare the clinical success, retention, and periodontal effect of traditional band-loop (TBL) SMs with 3D-printed SMs.

Design: Seventy children (mean age: 6.

Effects of solid and aqueous dietary diflubenzuron ingestion on some biological parameters in synthetic pyrethroid-resistant German cockroach, Blattella germanica L. (Blattodea: Ectobiidae).

Cockroaches, widespread pests found in metropolitan areas, are known as vectors of various disease agents, including viruses, fungi and antibiotic-resistant bacteria, as well as causing allergies in humans. Insect growth regulators have been used in pest management for several decades. These insecticides disrupt insect development and reproduction.

Exploring the Larvicidal and Repellent Potential of Taurus Cedar () Tar against the Brown Dog Tick ( sensu lato).

This study investigated the potential acaricidal and repellent effects of tar obtained from the Lebanon cedar ( A. Rich.) against the brown dog tick species sensu lato Latreille (Acari: Ixodidae).

Perioperative Nurses' Perceptions of the QSEN Competencies.

Since the development of the Quality and Safety Education for Nurses (QSEN) competencies, most published studies related to the topic have focused on investigating the perceptions of nursing faculty members, prelicensure and graduate nursing students, and recently graduated nurses regarding the competencies. Few researchers have explored practicing nurses' perceptions. The purpose of this study was to describe practicing perioperative nurses' perceptions of their knowledge, skills, and attitudes associated with the QSEN competencies.

Key Factors to Consider When Implementing an Advanced Practice Registered Nurse-Led Heart Failure Clinic.

Advanced practice registered nurses (APRNs) such as clinical nurse specialists and nurse practitioners excel at chronic disease management. Development of an APRN-led heart failure (HF) clinic is an ideal way to manage complex HF patients. However, there are important factors to consider when implementing an APRN-led HF clinic.

Evaluation of visceral adipose tissue thickness in precocious puberty.

Objective: Although there is a relationship between earlier onset of puberty and increased adiposity tissue. Publications in the literature on adiposis in patients with central precocious puberty (CPP) and visceral fat thickness (VFT) have conflicting results. So, in this study, we aimed to evaluate the relationship between sexual maturation and obesity in the development of early puberty and to examine their relationship with pelvic sonographic parameters.

Acute kidney injury in children with moderate-severe COVID-19 and multisystem inflammatory syndrome in children: a referral center experience.

Background: Data on the characteristics of acute kidney injury (AKI) in pediatric COVID-19 and MIS-C are limited. We aimed to define the frequency, associated factors and early outcome of AKI in moderate, severe or critical COVID-19 and MIS-C; and to present a tertiary referral center experience from Türkiye.

Methods: Hospitalized patients ≤ 18 years of age with confirmed COVID-19 or MIS-C at İhsan Doğramacı Children's Hospital, Hacettepe University, between March 2020-December 2021 were enrolled.

Familial Mediterranean fever: perspective on female fertility and disease course in pregnancy from a multicenter nationwide network.

The aim of this study was to analyze the pregnancy process, especially the Familial Mediterranean fever (FMF) disease course and attack types during pregnancy, and to examine the relationship between disease-related factors and female infertility in FMF patients. The study, which was planned in a multicenter national network, included 643 female patients. 435 female patients who had regular sexual intercourse were questioned in terms of infertility.