Publications by authors named "Cemile K Bicer"

Article Synopsis
  • The study aimed to evaluate how different flow rates of sevoflurane anesthesia (low, mid, and high) affect oxidative stress in surgical patients by measuring thiol and disulfide levels.
  • A total of 99 patients were randomly divided into three groups, each receiving varying fresh gas flow rates during anesthesia, with blood samples taken at different times to assess oxidative markers.
  • Results showed that mid-flow and low-flow anesthesia reduced disulfide levels compared to high-flow anesthesia, suggesting that low-flow anesthesia helps prevent oxidative damage in patients.
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Article Synopsis
  • The study examined the link between otitis media with effusion and oxidative stress, focusing on thiol/disulfide homeostasis.
  • It involved 30 patients with the condition and 35 healthy controls, revealing that the patients had lower levels of native and total thiols and higher levels of disulfides.
  • The findings suggest oxidative stress is a significant factor in the increased oxidized thiols in these patients, but further research is needed to confirm this relationship.
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Objective: To investigate novel oxidative stress marker thiol disulphide homeostasis in patients with acute myocardial infarction..

Methods: The case-control study was conducted at Yildirim Beyazit University, Ankara, Turkey, between October 26, 2015 and January 26, 2016.

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Objective: Herein, we investigated the balance of thiol/disulfide, with the hypothesis that the balance between disulfides and thiols, which are natural antioxidants, might be disrupted in patients with familial hypercholesterolemia, which eventually leads to endothelial damage.

Methods: In this study, we evaluated 51 patients diagnosed with familial hypercholesterolemia and 81 healthy subjects. Blood samples were taken from the patients after a minimum of 12 hours of fasting; samples were immediately centrifuged, stored in Eppendorf tubes, and preserved at -80°C.

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Conclusion: It is thought that oxidative stress may be the major cause of the increase in the oxide thiol form in the study group. The relationship between oxidative stress status and dynamic thiol/disulphide in nasal polyposis now needs to be investigated.

Objectives: The purpose of this study was to evaluate the relation between nasal polyposis and thiol/disulphide homeostasis, used as a marker of oxidative stress, by measuring that exchange using a novel technique.

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Aim: To evaluate the relationship between idiopathic recurrent pregnancy loss (RPL) and oxidative stress (OS) by means of thiol/disulfide homeostasis via a novel technique.

Methods: Thirty-nine pregnant women diagnosed with idiopathic RPL were compared with 50 healthy pregnant women without a history of abortion. Idiopathic RPL was defined as experiencing two or more consecutive miscarriages prior to 20 weeks of gestation with the presence of normal karyotypes of couple and/or abortus materials, negative maternal screening for anticardiolipin, anti β 2 glycoprotein antibodies and lupus anticoagulant, normal thyroid stimulating hormone, prolactin and hemoglobin A1C levels and normal pelvic sonography and/or hysterosalpingography.

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