Fecal microbiota transplantation is a rescue treatment modality for refractory ulcerative colitis.

Background: Fecal microbial transplantation (FMT) provides to replace beneficial bacteria with more favorable microbiomes in recipient with dysbiosis. The aim of the present study was to prospectively investigate the efficacy of FMT by assessing the clinical and endoscopic response in patients with ulcerative colitis (UC) who had failed anti-inflammatory and immunosuppressive therapy.

Methods: In this prospective and uncontrolled study, 30 patients with UC were included.