Machine learning predicts conventional imaging metastasis-free survival (MFS) for oligometastatic castration-sensitive prostate cancer (omCSPC) using prostate-specific membrane antigen (PSMA) PET radiomics.

Purpose: This study investigated imaging biomarkers derived from PSMA-PET acquired pre- and post-metastasis-directed therapy (MDT) to predict 2-year metastasis-free survival (MFS), which provides valuable early response assessment to improve patient outcomes.

Materials/methods: An international cohort of 117 oligometastatic castration-sensitive prostate cancer (omCSPC) patients, comprising 34 from John Hopkins Hospital (JHH) and 83 from Baskent University (BU), were treated with stereotactic ablative radiation therapy (SABR) MDT with both pre- and post-MDT PSMA-PET/CT scans acquired. PET radiomic features were analyzed from a CT-PET fusion defined gross tumor volume ((GTV) or zone 1), and a 5 mm expansion ring area outside the GTV (zone 2).

A Novel High Isolation 4-Port Compact MIMO Antenna with DGS for 5G Applications.

This paper presents the design and realization of a simple and low-profile, four-port multiple-input-multiple-output (MIMO) antenna operating in a mm-wave band supporting 5G communication technologies. As part of the design methodology, the initial stage involved the development of a conventional monopole patch antenna optimized for operation at 26 GHz, which was matched to a 50 Ω stepped feed line. Afterward, a square-shaped defected ground structure (DGS) with semi-circle slots on the edges was placed on the ground to improve the isolation, and the circular and rectangular slots were incorporated as DGSs to optimize the antenna impedance bandwidth.

Cellular Biomarkers in Mytilus galloprovincialis L. (Mediterranean Mussels) from Izmir Bay (Turkey).

In this study, cellular biomarkers and heavy metal concentration in the Mytilus galloprovincialis L. (Mediterranean mussels) collected from eight sites of Izmir Bay (Turkey) were determined to reveal water pollution for the first time in these stations. Results show that heavy metals (As, Cu, Hg, Zn, Cd, Sn, Pb) have been specified in mussels' tissues collected from all stations.

Prognostic values of ADC and SUV of the primary tumour in cervical cancer patients treated with definitive chemoradiotherapy.

We analysed the correlation of F-fluorodeoxyglucose uptake into primary tumours using the maximum standardised uptake value (SUV) and the mean apparent diffusion coefficient (ADC) values in magnetic resonance imaging (MRI) with the clinical and pathological factors in patients with cervical cancer who were treated with concurrent chemoradiotherapy. The patients were stratified according to the primary tumour pre-treatment ADC and SUV cut-off values. There were significant correlations between the SUV of the primary tumour and tumour size, and the treatment response.

Testicular tissue histology in rabbit testes after transparenchymal suturing with six different types of suture material.

Aim: Our aim was to investigate the changes in testicular tissue histology associated with six different types of commonly used suture material.

Materials And Methods: Twenty-one adult male New Zealand White rabbits were randomly assigned to seven groups of three animals each: sham-operated controls; polyglyconate suture; chromic catgut suture; polypropylene suture; polyglactin-910 suture; silk suture; and poliglecaprone-25 suture. All the materials tested were 6-0 caliber.

Evaluation of shockwave lithotripsy induced renal damage using heat shock protein 70 expression in the presence of different urinary obstruction periods.

Purpose: The aim of this study was to investigate the deleterious effects of shockwaves (SWs) using heat shock protein (HSP) 70 expression on obstructed kidneys with different obstruction periods.

Materials And Methods: Twenty-five rabbits were divided into two groups with 11 rabbits in each group. Both kidneys of the remaining three rabbits served as a sham group.

Does sildenafil affect uroflowmetry values in men with lower urinary tract symptoms suggestive of benign prostatic enlargement?

Aims: To investigate the effect of sildenafil on uroflowmetry values of patients with lower urinary tract symptoms (LUTS) suggestive of benign prostatic enlargement (BPE).

Methods: Thirty-eight consecutive patients and 15 control subjects without voiding symptoms were enrolled in the study. All patients underwent uroflowmetry testing thrice on different occasions.

Association of hypospadias with hypoplastic synpolydactyly and role of HOXD13 gene mutations.

Objectives: To present the association of hypospadias with hypoplastic synpolydactyly and discuss the molecular genetic basis of these conditions.

Methods: A large synpolydactyly kindred first described in 1995 was reinvestigated. Affected and unaffected subjects were interviewed, and pedigrees of the most recent generations were constructed.

Effect of carbon dioxide pneumoretroperitoneum on bacterial translocation in an experimental retroperitoneoscopy model.

Purpose: To evaluate the effect of artificial CO2 pneumoretroperitoneum on bacterial translocation in an experimental retroperitoneoscopy model.

Materials And Methods: Eighteen adult male New Zealand White rabbits weighing 2.5 to 3 kg were divided into two groups.

The effect of carbon dioxide pneumoretroperitoneum on free oxygen radicals in rabbit retroperitoneoscopy model.

The aim of this study was to investigate the possible effects of carbon dioxide (CO2) pneumoretroperitoneum on free oxygen radicals in the kidney. Twelve male New Zealand rabbits were divided into 2 equal groups; group 1; control operation group (retroperitoneal space preparation without CO2 insufflation) and group 2; study group (10-12 mm Hg pneumoretroperitoneum for 3 hours with CO2). At the end of the procedure, laparotomy was performed to harvest ipsilateral and contralateral kidney in both groups after three hours.

Sildenafil citrate does not alter ventricular repolarization properties: novel evidence from dynamic QT analysis.

Background: Sildenafil citrate may have direct cardiac electrophysiological effects, and is possibly responsible for some cardiac events. The aim of our study was to investigate the effects of sildenafil citrate on QT dynamicity properties with a new QT analysis program showing even small changes in ventricular repolarization.

Methods: Twenty-four-hour Holter electrocardiographic recordings were used to obtain the data in the predrug phase (1-hour rest position before drug administration), and in the postdrug phase (1-hour rest position, which began 60 minutes after 50 mg oral sildenafil citrate administration).

Plasma kinetic vaporization of the prostate: clinical evaluation of a new technique.

Purpose: We evaluated our results with bipolar plasma kinetic electrovaporization in the treatment of benign prostatic hyperplasia (BPH).

Patients And Methods: Twenty-one patients with infravesical obstruction by BPH have been treated with bipolar plasma kinetic electrovaporization. International Prostate Symptom Score (IPSS) with a quality of life (QOL) scoring questionnaire, uroflowmetry (maximum flow rate; Qmax), transrectal ultrasonography (TRUS), and residual urine volume and prostate specific antigen (PSA) measurements had been performed before surgery.

Effects of carbon dioxide pneumoretroperitoneum on free radical formation in remote organs and use of verapamil as an antioxidant.

Background And Purpose: Pneumoretroperitoneum (Prp) acts as an ischemia/reperfusion (I/R) model. Ischemia/reperfusion (I/R) injury causes production of reactive oxygen species, which affect organs remote from the sites of I/R. The aim of this study was to assess the remote organ changes after Prp and to explore the effects of antioxidants.

Extracorporeal shockwave lithotripsy for solitary distal ureteral stones: does the degree of urinary obstruction affect success?

Background And Purpose: Extracorporeal shockwave lithotripsy (SWL) is a safe and effective way to treat stones in the distal ureter, but the impact of urinary obstruction on outcome is not clear. We investigated the relation between the degree of stone-induced urinary obstruction and the outcome of SWL treatment in patients with solitary distal ureteral stones.

Patients And Methods: A series of 165 consecutive patients with solitary distal ureteral stones underwent SWL (Multimed 9200 Lithotriptor, Elmed Medical Systems, Turkey) between October 2002 and September 2003 at two separate centers.

Comparison of changes in tissue oxidative-stress markers in experimental model of open, laparoscopic, and retroperitoneoscopic donor nephrectomy.

Purpose: We evaluated the oxidative stress in renal tissue during three types of surgery: open donor nephrectomy (ODN), laparoscopic donor nephrectomy (LDN), and retroperitoneoscopic donor nephrectomy (RDN). The aim was to find out which is the appropriate procedure for harvesting a donor kidney.

Materials And Methods: Twenty-four New Zealand White rabbits were randomized to four groups, each consisting of six rabbits.

Effect of retroperitoneoscopic donor nephrectomy on tissue oxidative stress markers in rabbit pneumoretroperitoneum model.

Background And Purpose: Laparoscopic donor nephrectomy causes increased renal oxidative stress. There are no data about the effects of the retroperitoneoscopic route. The aim of our study was to evaluate the oxidative stress occurring in renal tissues during retroperitoneoscopic donor nephrectomy in a rabbit model.