Exposure to environmental tobacco smoke (ETS) during early childhood increases the risk of developing asthma. The intention of this study was to genotype a population of children from Coahuila state in Northern Mexico and to determine whether polymorphisms of the CYP1A1, GSTP1, and IL13 genes are associated with exposure to ETS and subsequently a higher risk for asthma. IL13 plays an important role in the development of allergic response, particularly those related with airway inflammation.
View Article and Find Full Text PDFInorganic arsenic (i-As) is an environmental carcinogen to which millions of people are chronically exposed mainly via drinking water. In this study, we used the comet assay to evaluate DNA damage in i-As-exposed inhabitants of the north of Mexico. The environmental monitoring and the exposure assessment were done by measuring both drinking water arsenic (As) content and total urinary As.
View Article and Find Full Text PDFBackground: Bronchial asthma is the most common chronic disease in children, producing the highest absenteeism among children and adults.
Objective: To determine the relation between respiratory function in asthmatic children and contaminant and climatic environmental factors.
Material And Methods: It was performed a study with 26 asthmatic patients, from the Immuno-Allergies Department of the Specialties Hospital no.