Publications by authors named "Celine Zumkeller"
The development of novel DNA assembly methods in recent years has paved the way for the construction of synthetic replicons to be used for basic research and biotechnological applications. A learning-by-building approach can now answer questions about how chromosomes must be constructed to maintain genetic information. Here we describe an efficient pipeline for the design and assembly of synthetic, secondary chromosomes in Escherichia coli based on the popular modular cloning (MoClo) system.
View Article and Find Full Text PDFDraft genome sequence of sp. PAP.153, isolated from a marine sponge in Papua, Indonesia.
Microbiol Resour Announc
June 2024
Article Synopsis
- sp. PAP.153 is a microorganism that was extracted from a marine sponge.
- The researchers have sequenced its draft genome, which is 4.12 million base pairs long.
- They evaluated the organism's ability to produce specialized metabolites, particularly emphasizing the production of flexirubin, an important chemical marker.
Draft genome sequences of 21 strains isolated from amphibian specimens.
Microbiol Resour Announc
April 2024
Article Synopsis
- The genomes of 21 strains from European salamanders and various Madagascan frog species were sequenced using Illumina technology.
- The resulting draft genome sequences range in size from approximately 4.7 to 7.2 megabases (Mbp).
- This work aims to facilitate comparative genomics and help classify these strains taxonomically.
Draft Genome Sequence of sp. Strain PAP.21, Isolated from a Coast Sample of Papua, Indonesia.
Microbiol Resour Announc
April 2023
sp. strain PAP.21 (EXT111902) was isolated from the coast of Cenderawasih Bay National Park in West Papua, Indonesia.
View Article and Find Full Text PDFMicrobial communities in the immediate environment of socialized invertebrates can help to suppress pathogens, in part by synthesizing bioactive natural products. Here we characterized the core microbiomes of three termite species (genus ) and their nest material to gain more insight into the diversity of termite-associated bacteria. Sampling a healthy termite colony over time implicated a consolidated and highly stable microbiome, pointing toward the fact that beneficial bacterial phyla play a major role in termite fitness.
View Article and Find Full Text PDFThe development of novel DNA assembly methods in recent years has paved the way for the construction of synthetic replicons to be used for basic research and biotechnological applications. Questions of how chromosomes need to be constructed to maintain the genetic information can now be answered by a learning-by-building approach. Here, we describe an efficient pipeline for the design and assembly of synthetic, secondary chromosomes in Escherichia coli based on the popular Modular Cloning system (MoClo).
View Article and Find Full Text PDFLearning by building is one of the core ideas of synthetic biology research. Consequently, building synthetic chromosomes is the way to fully understand chromosome characteristics. The last years have seen exciting synthetic chromosome studies.
View Article and Find Full Text PDFBackground: In allergic asthma, IgE increases airway remodelling but the mechanism is incompletely understood. Airway remodelling consists of two independent events increased cell numbers and enhanced extracellular matrix deposition, and the mechanism by which IgE up-regulates cell proliferation and extracellular matrix deposition by human airway smooth muscle cells in asthma is unclear.
Objective: Characterise the role of the two IgE receptors and associated signalling cascades in airway smooth muscle cell remodelling.