Relation between pretransplant magnesemia and the risk of new onset diabetes after transplantation within the first year of kidney transplantation.

Background: New-onset diabetes after transplantation (NODAT) is a frequent condition associated with a poor outcome. In kidney transplantation, hypomagnesemia is a frequent posttransplant complication and has been associated with calcineurin inhibitors use. Previous studies have analyzed the relationship between posttransplant hypomagnesemia and the risk of NODAT and provided conflicting conclusions.

Long-term maintenance immunosuppressive regimen with tacrolimus monotherapy.

Background: The long-term outcome of kidney transplant recipients on monotherapy with calcineurin inhibitors has been poorly analyzed. This study aimed to describe the long-term outcome of patients on Tac monotherapy (mTac) and to compare this regimen to a standard dual therapy with Tac/MMF.

Material And Methods: This retrospective study included 84 consecutive first kidney recipients transplanted between 1998 and 2003 and followed until 2010.

[Prospective observational study of drug-induced hyperkalemia in hospitalized non dialized adult patients].

Objective: To study the incidence and risk factors of drug-induced hyperkalemia in adult, hospitalized patients.

Methodology: A three months prospective observational study was used including all hospitalized, non dialyzed, patients older than 17 years who presented with a hyperkalemia egal or over 6 mmol/L. The studied variables were demographic, clinical, biological and therapeutic.

Absence of renal lesions in C57BL/KaLwRij mice with advanced myeloma due to 5T2MM cells.

Renal failure is one of the main complications in multiple myeloma (MM) and histopathological lesions are due to light chains accumulation in the kidney. The 5T2MM mouse model closely mimics osteolytic lesions observed in clinics. We studied the occurrence of pathological changes in the kidney of mice inoculated with 5T2MM myeloma cells.