Publications by authors named "Celine M Schreidah"
Article Synopsis
- Regular use of OTC sunscreen is crucial for preventing skin cancer, but it is rarely covered by Medicaid plans across the U.S.
- A review of 111 Medicaid preferred drug lists revealed that only five states cover sunscreen, putting a financial burden on low-income individuals and families.
- The text analyzes the current Medicaid policies on sunscreen coverage and estimates the costs related to this essential skin cancer prevention method.
Article Synopsis
- - The most common types of liposarcomas are well-differentiated and dedifferentiated liposarcomas, usually found in the deep retroperitoneum or extremities, while atypical lipomatous tumors (ALT) are rare and less studied when located superficially.
- - A case study of a 54-year-old man revealed an ALT on his left upper back that had unusual characteristics, including significant pleomorphism and specific gene amplifications, which sets it apart from typical ALT cases reported.
- - The report discusses the diagnostic process and histopathological findings of the tumor, while providing an overview of different liposarcoma subtypes and management strategies.
Article Synopsis
- Lichen sclerosus et atrophicus (LSA) is a chronic skin condition primarily affecting female genitalia, while morphea is a rare inflammatory skin disorder characterized by hard skin patches.
- There is an ongoing debate among researchers about whether LSA and morphea are related or separate conditions, particularly when they occur in the same patient.
- A case is reported involving a 62-year-old woman with both extragenital LSA-morphea overlap in her inguinal folds and subsequent development of genital LSA three months later, highlighting the rare progression between these two conditions that had not been previously documented.
Article Synopsis
- Researchers investigated cases of lymphoproliferative disorders (LPDs) and cutaneous lymphomas that appeared after COVID-19 vaccination, examining the link between specific vaccines and these reactions.
- They found 50 biopsy-proven cases primarily from the U.S., Italy, and Greece, with the Pfizer-BioNTech vaccine associated with 72% of these instances.
- Most patients experienced favorable outcomes, with a common form being lymphomatoid papulosis, and treatment options varied from observational care to medication like steroids and methotrexate.
Article Synopsis
- Skin cancer mortality rates are on the rise, emphasizing the need for survival analysis to identify at-risk individuals and effective interventions.
- Current statistical methods struggle to integrate diverse data types (e.g., genetics, demographics) and predictive algorithms, limiting their effectiveness.
- Advances in AI, including supervised and unsupervised learning, hold promise for improving skin cancer survival analysis, though most studies focus on melanoma, indicating a need for broader research on various skin cancers and the combination of different data types.
The etiology of CTCL is a subject of extensive investigation. Researchers have explored links between CTCL and environmental chemical exposures, such as aromatic hydrocarbons (eg, pesticides and benzene), as well as infectious factors, including various viruses (eg, human T-lymphotropic virus [HTLV]-I and HTLV-II) and bacteria (eg, Staphylococcus aureus). There has been growing emphasis on the role of malignant inflammation in CTCL development.
View Article and Find Full Text PDFMonoclonal Gammopathy of Undetermined Significance (MGUS) is a clonal plasma cell disorder that is considered preneoplastic, asymptomatic, and only requiring observation. However, MGUS may result in cutaneous complications, which are poorly understood, causing treatment delays and patient suffering. We present 30 patients with cutaneous findings associated with MGUS, characterizing clinical presentations, isoforms, treatments, and outcomes.
View Article and Find Full Text PDFTebentafusp is a bispecific protein that recently underwent FDA approval for the treatment of metastatic uveal melanoma that functions by redirecting cytotoxic T cells to glycoprotein-100, a protein highly expressed in melanoma. Although clinical trials have demonstrated that rashes are common in the first few days of treatment, little is known about skin reactions that develop later in the treatment course. Herein, we describe a type IV hypersensitivity reaction and vitiligo-like depigmentation that developed six weeks into treatment and discuss the possible mechanisms underlying these reactions.
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- Mucha-Habermann disease (MHD) is an inflammatory skin condition with symptoms resembling cutaneous T-cell lymphoma, while its severe variant, febrile ulceronecrotic MHD (FUMHD), presents with systemic symptoms and ulcers.
- A case study of a 21-year-old woman showed atypical lymphomatoid features of FUMHD alongside hemophagocytic lymphohistiocytosis (HLH), leading to significant clinical findings and a biopsy that indicated atypical CD8 + lymphocyte infiltration.
- Treatment using etoposide and dexamethasone resulted in rapid improvement of her symptoms, with the patient's skin lesions healing over time and confirming the MHD diagnosis; she has remained
With recent advances in understanding racial, socioeconomic, and mental health issues in medicine and their relation to policy and legislation, medical professionals are increasingly involved in local and national advocacy efforts. At the frontlines of these initiatives are medical students who, in addition to completing required coursework and clinical training, devote themselves to serving patients through civic participation. The burgeoning evidence concerning health care disparities and inequity, along with greater awareness of racial and socioeconomic discrimination, have made advocacy an essential aspect of many students' medical training.
View Article and Find Full Text PDFIntroduction: Cutaneous T-cell lymphoma (CTCL) is a heterogenous group of non-Hodgkin lymphomas. Similar presentation to benign conditions, significant genetic variation, and lack of definitive biomarkers contributes to diagnostic delay. The etiology of CTCL is unknown, and environmental exposures, such as geographic, occupational, chemicals, sunlight, and insects have been investigated.
View Article and Find Full Text PDFIndividual reports described lymphoproliferative disorders (LPDs) after COVID-19 vaccination; however, the relationship between cases is unexamined. We aim to determine if there are cases of cutaneous LPDs associated with COVID-19 vaccination and their outcomes. We present a review of world literature, vaccine registries, and two unreported cases of LPDs after COVID-19 vaccination.
View Article and Find Full Text PDFBackground: Patients facing a cutaneous lymphoma diagnosis frequently turn to the internet for information but finding patient-accessible education may be a challenge.
Objective: To investigate accessibility and readability of patient-oriented online education on cutaneous lymphomas, including cutaneous T-cell and B-cell lymphoma subtypes.
Methods: This study queried a search engine for 11 cutaneous lymphoma terms, resulting in 1083 webpages.
Decision paralysis (DP) can be defined as a patient's inability to commit to a physician and/or initiate appropriate treatment for their condition. An incessant search for greater physician opinions often leads to treatment delay, disease progression, and initiation of care at more advanced stages. Despite the harms associated with DP, a dearth of research on the issue remains.
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