Organophosphate pesticide residues in fruits and vegetables in Nigeria: prevalence, environmental impact, and human health implications.

Pesticides have become indispensable in modern agriculture, aiding in crop protection, and ensuring food security. However, their extensive use has raised concerns about environmental contamination and human health risks. This manuscript reviews the prevalence of organophosphate pesticide (OPP) use in Nigerian agriculture and explores methods for detecting pesticide residues in fruits and vegetables.

Structure-based molecular networking, molecular docking, dynamics simulation and pharmacokinetic studies of for identification of potential inhibitors against selected cancer targets.

The rationale at the basis of targeted approach in oncology is radically shifting-from development of highly specific agents aiming at a single target towards molecules interfering with multiple targets. This study was performed to isolate and characterize bioactive molecules from stem and investigate their potentials as multi-targeted inhibitors against selected non-small cell lung cancer, breast cancer and chronic myelogenous leukemia oncogenic targets. Three compounds: β-sitosterol (), α-amyrin () and stigmasterol () were isolated.

GC/MS analysis of polynuclear aromatic hydrocarbons in sediment samples from the Niger Delta region.

Thirteen sediment samples from different locations in the Niger Delta region of Nigeria were analyzed for the presence of 16 polynuclear aromatic hydrocarbons (PAHs) via gas chromatography/mass spectrometry. The specific target compounds for this study included naphthalene, acenaphthylene, acenaphthene, flourene, phenanthrene, anthracene, flouranthene, pyrene, benz[a]anthracene, chrysene, benzo[b]fluoranthene, benzo[k]flouranthene, benzo[a]pyrene, benzo[ghi]perylene, dibenz[a,h]anthracene, and indeno[1,2,3-cd]pyrene. Four isotopically labeled polynuclear aromatic hydrocarbons (acanaphthene-d10, phenanthrene-d10, chrysene-d12 and perylene-d12) were used for internal standardization.