Genetic Labeling of Cells Allows Identification and Tracking of Transgenic Platelets in Mice.

Background: The use of knock-out mouse models is crucial to understand platelet activation and aggregation.

Methods: Analysis of the global double fluorescent Cre reporter mouse that has been crossbred with the megakaryocyte/platelet specific mouse.

Results: Platelets show bright ( negative) and ( positive) fluorescence.