Publications by authors named "Celia del Agua"

Article Synopsis
  • * Researchers used single-domain nanobodies from camels to target a specific enzyme (β-1,3-glucanosyltransferases) crucial for fungal survival, revealing important structural insights.
  • * The tested nanobody showed strong antifungal effects in laboratory settings and in animal models, particularly against certain strains of C. neoformans, suggesting it could be a promising avenue for developing new antifungal therapies.
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Purpose: Non-small cell lung cancer (NSCLC) is one the types of cancer with higher prevalence and mortality. Apo2-Ligand/TRAIL is a TNF family member able to induce apoptosis in tumor cells but not in normal cells. It has been tested in clinical trials against different types of human cancer including NSCLC.

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Tracheobronchial submucous glands can be considered the pulmonary equivalent of minor salivary glands and therefore they can develop most of the tumours originated in these. Nevertheless, in spite of the wide distribution of this kind of glands along the tracheobronchial tree, pulmonary salivary gland-like neoplasms are not very frequent. Among them, the most frequent are mucoepidermoid and adenoid cystic carcinomas.

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Objective: To study the evolution of 64 patients initially diagnosed with ASAP (atypical small acinar proliferation).

Material And Methods: Between 1998 and the end of 2003, 64 patients were diagnosed at our centre with ASAP.

Results: The mean age of the patients assessed was 69 years (SD 6.

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