Publications by authors named "Celia Zinger-Salmun"
Eur J Paediatr Neurol
November 2023
Article Synopsis
- Angelman Syndrome (AS) is a rare neurogenetic disorder impacting intellectual and motor functions, creating challenges in assessing its severity and treatment responses, prompting the need for specialized rating scales.
- The Clinical Global Impressions scale was adapted for AS, called CGI-S-AS and CGI-I-AS, and was utilized in a trial of the drug gaboxadol to evaluate its effectiveness in managing the condition.
- Validation of the CGI-I-AS showed it aligns well with other rating scales, highlighting effective monitoring of sleep symptoms, while also underscoring areas needing improvement in assessing communication-related effects.
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