Publications by authors named "Celia Mamma"
Article Synopsis
- High-resolution anoscopy (HRA) is crucial in identifying precursors to anal squamous cell carcinoma, and AI models show potential for improving this process, though previous studies haven't looked at how staining and anal manipulation affect them.
- A convolutional neural network was created using 27,770 images to distinguish between high-grade and low-grade lesions, achieving an impressive overall accuracy of 98.3% across various image subsets.
- The AI demonstrated standout sensitivity and specificity, and its effectiveness varied based on the type of staining used, suggesting that AI could significantly enhance the accuracy and efficiency of HRA procedures in real time.
Article Synopsis
- Traumatic brain injury (TBI) can cause serious inflammation in the brain by activating special cells called microglia.
- A study looked at how a specific protein (TSPO) helps track this activation using special imaging and tests on mice with mild TBI.
- The results showed that while microglia do increase after injury, they're not the only cells affecting the TSPO levels, suggesting that TSPO might not be the best way to track microglial activity alone.
Traumatic brain injury (TBI) is a leading cause of death and disability all over the world. TBI leads to (1) an inflammatory response, (2) white matter injuries and (3) neurodegenerative pathologies in the long term. In humans, TBI occurs most often in children and adolescents or in the elderly, and it is well known that immune responses and the neuroregenerative capacities of the brain, among other factors, vary over a lifetime.
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