Solvent-assisted dispersive micro-solid phase extraction of bisphenols using iron(III) thenoyltrifluoroacetonate complex (Fe(TTA)) as a new nanostructured sorbent: a proof of concept.

In this work, we describe for the first time the use of iron(III) thenoyltrifluoroacetonate complex (Fe(TTA)) as a novel sorbent for solvent-assisted dispersive micro-solid phase extraction (SA-dμSPE) of bisphenols from water samples. The extraction procedure is based on the formation of nanoparticles following the rapid injection of a methanolic solution of Fe(TTA) into the stirred aqueous sample. Herein, the synthesis of Fe(TTA) and study of the essential parameters of the preparative procedure are described.

Renewable sorbent dispersive solid phase extraction automated by Lab-In-Syringe using magnetite-functionalized hydrophilic-lipophilic balanced sorbent coupled online to HPLC for determination of surface water contaminants.

An automated methodology for magnetic dispersive solid phase microextraction integrating bead injection approach for renewable sorbent introduction is presented for the first time and was successfully applied to the enrichment of water contaminants. For this purpose, a simple procedure was developed for the functionalization of commercial SupelTM-Select HLB (Hydrophilic modified styrene polymer) sorbent beads that allowed embedding magnetite nanoparticles (FeO). The sorbent was then used in a dispersive solid phase extraction procedure that was carried out entirely inside the void of an automatic syringe pump following the flow-batch concept of Lab-In-Syringe including automated renewal of the sorbent for each analysis.

Lab-In-Syringe with Bead Injection Coupled Online to High-Performance Liquid Chromatography as Versatile Tool for Determination of Nonsteroidal Anti-Inflammatory Drugs in Surface Waters.

We report on the hyphenation of the modern flow techniques Lab-In-Syringe and Lab-On-Valve for automated sample preparation coupled online with high-performance liquid chromatography. Adopting the bead injection concept on the Lab-On-Valve platform, the on-demand, renewable, solid-phase extraction of five nonsteroidal anti-inflammatory drugs, namely ketoprofen, naproxen, flurbiprofen, diclofenac, and ibuprofen, was carried out as a proof-of-concept. In-syringe mixing of the sample with buffer and standards allowed straightforward pre-load sample modification for the preconcentration of large sample volumes.