Publications by authors named "Celal Saglam"
Specific Granule Deficiency Due To Novel Homozygote Variant.
Pediatr Allergy Immunol Pulmonol
March 2022
Specific granule deficiency (SGD) is a rare immunodeficiency associated with gene variants. It can cause severe recurrent infections and is lethal without successful stem cell transplantation. Few cases with SGD of both type 1 and type 2 have been described in the literature.
View Article and Find Full Text PDFGrowth curves for Turkish Girls with Turner Syndrome: Results of the Turkish Turner Syndrome Study Group.
J Clin Res Pediatr Endocrinol
September 2015
Article Synopsis
- * Researchers analyzed height and weight data from 842 TS patients under 18 years old before they started any treatment, calculating growth percentiles for different age groups.
- * The resulting national growth charts will help monitor and manage growth in Turkish girls with TS, aiding in their treatment with growth-promoting therapies.
Article Synopsis
- The study aimed to validate pediatric diagnostic criteria for familial Mediterranean fever (FMF) using a large international registry and compare their effectiveness with older criteria.
- The research involved 339 FMF patients and 377 control patients with other periodic fever disorders, analyzing the performance of Yalcinkaya-Ozen, Tel Hashomer, and Livneh criteria.
- The Yalcinkaya-Ozen criteria showed the highest sensitivity (87.4%) but lower specificity (40.7%) compared to Tel Hashomer and Livneh criteria, making it a useful diagnostic tool for pediatric FMF despite its limitations in specificity.
Purpose: Necrotizing enterocolitis (NEC) is a severe disease of mostly premature infants with high morbidity and mortality rates. There is no reliable biomarker for detecting newborns at risk for NEC development. We aimed to investigate small intestinal lactoferrin (LF) and calprotectin (CAL) levels as predictors and indicators of disease severity in an experimental newborn rat model.
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