Publications by authors named "Cediel G"

Aims: To investigate the distribution of left atrioventricular coupling index (LACI) among patients with heart failure and left ventricular ejection fraction (LVEF)<50% and to explore its association with the combined endpoint of all-cause death or HF hospitalization at long term follow-up.

Methods And Results: Patients with HF and LVEF<50% undergoing cardiac magnetic resonance (CMR) were evaluated. Patients with atrial fibrillation or flutter were excluded.

View Article and Find Full Text PDF

Objective: To analyze the consumption of critical nutrients and other sweeteners, according to the degree of food processing in the population of Antioquia.

Methods: Cross-Sectional Study. The dietary intake of 4,382 participants of the Perfil Alimentario y Nutricional de Antioquia 2019 (Antioquia Food and Nutrition Profile 2019) was evaluated.

View Article and Find Full Text PDF
Article Synopsis
  • The PERISCOPE Phase I clinical trial assessed the safety of PeriCord, a tissue graft made from decellularised pericardial matrix and umbilical cord mesenchymal cells, in patients undergoing surgical revascularization after non-acute myocardial infarction.
  • In the trial, seven patients received PeriCord and demonstrated no adverse effects during the one-year follow-up, although there were no significant changes in overall quality of life or cardiac function compared to controls.
  • The study highlighted PeriCord's immunomodulatory effects, specifically in influencing the behavior of circulating monocytes towards a repair-promoting state, indicating potential for further exploration in treating inflammation-related conditions.
View Article and Find Full Text PDF

Background: Limited data are available on the long-term trajectory of estimated glomerular filtration rate (eGFR) in patients with chronic heart failure.

Objectives: The authors evaluated eGFR dynamics using the 2009 Chronic Kidney Disease Epidemiology Collaboration equation and its prognostic significance in a real-world cohort over a 15-year follow-up.

Methods: A prospective observational registry of ambulatory heart failure outpatients was conducted, with regular eGFR assessments at baseline and on a 3-month schedule for ≤15 years.

View Article and Find Full Text PDF

Aims: To assess the agreement between left ventricular end-diastolic diameter index (LVEDDi) and volume index (LVEDVi) to define LV dilatation and to investigate the respective prognostic implications in patients with heart failure (HF).

Methods And Results: Patients with HF symptoms and LV ejection fraction (LVEF) < 50% undergoing cardiac magnetic resonance were evaluated retrospectively. LV dilatation was defined as LVEDDi or LVEDVi above the upper normal limit according to published reference values.

View Article and Find Full Text PDF

Introduction: Ultra-processed food products (UPF) have been related to chronic diseases (CD). Public health politics has been establishing strategies to decrease the consumption of these products in the country.

Objectives: i) To assess the trend of the consumption of UPF between 2005 and 2015.

View Article and Find Full Text PDF

Worsening heart failure (HF) is a vulnerable period in which the patient has a markedly high risk of death or HF hospitalization (up to 10% and 30%, respectively, within the first weeks after episode). The prognosis of HF patients can be improved through a comprehensive approach that considers the different neurohormonal systems, with the early introduction and optimization of the quadruple therapy with sacubitril-valsartan, beta-blockers, mineralocorticoid receptor antagonists, and inhibitors. Despite that, there is a residual risk that is not targeted with these therapies.

View Article and Find Full Text PDF

Introduction And Objectives: The present study sought to establish the diagnostic yield of cardiovascular magnetic resonance (CMR) in a large cohort of patients admitted with myocardial infarction (MI) with nonobstructive coronary artery disease (MINOCA) based on the timing of referral to CMR.

Methods: Consecutive patients referred to CMR from January 2009 to February 2022 with a working diagnosis of MINOCA were retrospectively evaluated. Cine, T-weighted, early, and late gadolinium-enhanced images were acquired and analyzed.

View Article and Find Full Text PDF

Purpose: This cross-sectional study aimed to assess the association between ultra-processed foods consumption and dietary diversity and micronutrient intake in Australia.

Methods: As part of the Nutrition and Physical Activity Survey (2011-2012), 12,153 participants aged 2 years and above were recruited and interviewed. Dietary intake data were collected by two 24-h dietary recalls using the Automated Multiple-Pass Method.

View Article and Find Full Text PDF

Ultra-processed foods (UPFs) are associated with deterioration in dietary quality and the development of chronic diseases. The NOVA score, developed in Brazil to assess UPF consumption quickly and inexpensively, is adapted and validated here using a sample of 203 young women from Medellín, Colombia. Food consumption was evaluated using 24-hour dietary recall and with the NOVA-UPF score.

View Article and Find Full Text PDF

Background: Age-specific and gender-specific reference values for left ventricular (LV) and right ventricle volumes are available. The prognostic implications of the ratio between these volumes in heart failure and preserved ejection fraction (HFpEF) have never been evaluated.

Methods: We examined all HFpEF outpatients undergoing a cardiac magnetic resonance from 2011 to 2021.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigated whether the PCSK9 inhibitor evolocumab could reduce troponin levels in patients with stable heart failure with reduced ejection fraction (HFrEF) of ischaemic origin, suggesting a potential to limit disease progression.* -
  • Conducted over one year, the trial compared the effects of evolocumab plus guideline-directed medical therapy (GDMT) against GDMT alone, finding no significant change in troponin levels but noted decreases in NT-proBNP and ST2 levels in the intervention group.* -
  • Results indicated a significant reduction in total and LDL cholesterol in the evolocumab group, while PCSK9 levels also increased, although the overall findings were limited and do not establish clear
View Article and Find Full Text PDF

Subjects with type 2 diabetes mellitus (T2D) are at increased risk for heart failure (HF). The cardiac-specific (FABP3) and adipose-tissue-specific (FABP4) types of the fatty acid binding proteins have been associated with both all-cause and cardiovascular (CV) mortality. The aim of this study was to explore the prognosis value of FABP3 and FABP4 in ambulatory subjects with chronic HF (CHF), with and without T2D.

View Article and Find Full Text PDF
Article Synopsis
  • The study focused on the use of intracoronary pressure wires in guiding treatment for patients with coronary artery disease, aiming to assess changes in diagnosis, treatment strategies, and clinical outcomes.
  • Involving 1,414 patients and observing 1,781 lesions, the study found significant changes in the extent of coronary disease and treatment plans, with over half of the patients experiencing adjustments after using the pressure wire.
  • The findings indicated that using the pressure wire was generally safe and led to a lower incidence of major adverse cardiovascular events (MACE), particularly when percutaneous coronary intervention (PCI) was the initial treatment strategy.
View Article and Find Full Text PDF
Article Synopsis
  • Myocardial fibrosis can worsen prognosis in heart failure patients, even if they show left ventricular reverse remodeling (LVRR) after treatment.
  • This study analyzed the levels of specific collagen-derived peptides in 1,034 heart failure patients to evaluate their association with heart function recovery and overall outcomes.
  • Results showed that patients with low levels of procollagen type I C-terminal propeptide (PICP) had better heart function improvements and lower risks of heart failure-related issues, especially in women and nonischemic cases.
  • The findings suggest that measuring PICP levels could help identify patients who are more likely to respond positively to treatment and enhance their clinical outcomes.
View Article and Find Full Text PDF

Objective: To assess the association between the consumption of ultra-processed foods (UPF) and diet quality among preschool children and women of reproductive age from Argentina.

Design: Cross-sectional and nationally representative survey. The food items were classified according to the NOVA system.

View Article and Find Full Text PDF

Background: The prediction of sudden cardiac death (SCD) in heart failure (HF) remains an unmet need. The aim of our study was to assess the prevalence of SCD over 20 years in outpatients with HF managed in a Mediterranean multidisciplinary HF Clinic, and to compare the proportion of SCD (SCD/all-cause death) to the expected proportional occurrence based on the validated Seattle Proportional Risk Model (SPRM) score.

Methods And Results: This prospective observational registry study included 2772 outpatients with HF admitted between August 2001 and May 2021.

View Article and Find Full Text PDF

Background: There is an urgent need for cost-effective strategies to promote quality of life in patients with heart failure (HF). Several studies reported benefits in HF prognosis for marine omega-3 fatty acids and plant-based dietary patterns.

Objectives: The aim of this study was to explore whether dietary alpha-linolenic acid (ALA), the main plant omega-3, relates to a better HF prognosis.

View Article and Find Full Text PDF