A time trade-off study in the UK, Canada and the US to estimate utilities associated with the treatment of haemophilia.

Introduction: Haemophilia is a rare bleeding disorder caused by a deficient or absent clotting factor, leading to frequent bleeding. Multiple intravenous (IV) infusions have been the standard prophylactic treatment; however, newer treatment options involve less frequent subcutaneous (SC) injections. To inform future health economic evaluations, this study applied the time trade-off (TTO) method for estimation of utilities associated with haemophilia treatment for both people with the disease and potential caregivers.

Preferences for different treatment options among people living with acromegaly in the US.

Objective: Acromegaly is a rare hormonal disorder that results in enlargement of the face, hands and feet. It is associated with comorbidities, increased mortality, reduced quality of life and economic burden. Adequate treatment is critical to alleviate symptoms; however, the treatment burden is substantial.

Perceptions, behaviours and potential barriers to effective obesity care. Results from the ACTION-DK study.

Aim: Weight bias, stigma and discrimination are pervasive in the health care system and society and may result in biased treatment of people living with obesity (PwO). We aimed to identify perceptions, attitudes and potential barriers that exist between people with obesity and health care professionals (HCPs) in Denmark.

Methods: The ACTION-DK survey was a cross-sectional, non-interventional, descriptive study conducted in Denmark.

Utilities associated with stoma-related complications: peristomal skin complications and leakages.

Aim: Peristomal skin complications (PSCs) and leakages are major issues for people living with a stoma. The purpose of this study is to understand how these stoma-linked complications impact health-related quality of life (HRQoL) in a UK population.

Materials And Methods: The study used time trade-off (TTO) methodology to quantify health state utilities associated with two stoma-related complications: PSC and leakages.

Costs of the COVID-19 pandemic associated with obesity in Europe: A health-care cost model.

Excess weight is associated with severe outcomes of coronavirus disease 2019 (COVID-19). We aimed to estimate the total secondary care costs by body mass index (BMI, kg/m ) category when hospitalized due to COVID-19 in Europe during the first wave of the pandemic from January to June 2020. Building a health-care cost model, this study aimed to estimate the total costs of COVID-19.

Costs of COVID-19 pandemic associated with diabetes in Europe: a health care cost model.

Objective: Diabetes is associated with progression to severe COVID-19. The objective of this study was to estimate to what extent the increased risk among people with diabetes could impact the secondary care costs of COVID-19 throughout Europe during the first wave of the COVID-19 pandemic from January to June 2020.

Methods: Applying a health care cost model based on inputs from data published in international peer-reviewed journals, identified via a rapid literature review this study aimed to estimate the total secondary sector costs of COVID-19.