Efficacy of the Spiration Valve System in Patients with Severe Heterogeneous Emphysema: A Systematic Review and Meta-Analysis.

Background: Spiration Valve System (SVS) is an alternative for patients with severe heterogeneous emphysema; however, data about efficacy from randomized controlled trials (RCT) are unclear.

Objectives: To explore both efficacy and safety of SVS in patients with severe emphysema and hyperinflation.

Methods: We included PubMed, EMBASE, Coch-rane database.

Bronchoscopic Lung Volume Reduction with Endobronchial Zephyr Valves for Severe Emphysema: A Systematic Review and Meta-Analysis.

Background: Endoscopic lung volume reduction using Zephyr® valves has been recently adopted as a treatment option for patients with severe emphysema without collateral ventilation (CV).

Objectives: To assess the efficacy and safety of Zephyr valves in such a population.

Methods: Studies were identified from MEDLINE and EMBASE databases.