Qualitative analysis of the acetogenins from (Annonaceae) leaves by HPLC-Q-Orbitrap and their antibacterial potential against oral pathogens.

Araticum is an edible and appreciable fruit of , which is popularly known as a traditional herb in the Brazilian cerrado. A phytochemical study from the leaves of showed that HPLC-ESI-Q-Orbitrap® provided through PRM experiments (MS) is an efficient method for the fast and accurate analysis of a complex mixture of annonaceous acetogenins, with the identification of sylvaticin and gigantetrocin-A type acetogenins for the first time. In addition, the crude leaf extract and acetogenin-rich fractions were assayed against , , and strains, which are usually related to oral infections.