Publications by authors named "Cecilia Man Ching Tang"
Article Synopsis
- The study found extensive changes in chromosome 9 among 34 patients with esophageal squamous cell carcinoma, using 17 genetic markers to measure loss of heterozygosity (LOH).
- LOH rates varied significantly, ranging from 42.9% to 80%, with three major regions consistently deleted: 9p23-p22, 9q13-q22.3, and 9q34.
- Specific LOH patterns were linked to tumor differentiation, while the research indicated that drinking habits do not significantly influence the risk of esophageal cancer in Chinese individuals.
Esophageal cancer (ESC) is an important cancer worldwide. Chromosome 11 plays an important role in the development of several human cancers. In this study, 19 polymorphic microsatellite markers spanning the whole chromosome 11 were used to screen for loss of heterozygosity (LOH) in 38 primary esophageal squamous cell carcinomas.
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