Ibrutinib-related uveitis: A case series.

Purpose: Four cases of ibrutinib-related uveitis are presented, which are to the best of our knowledge the first in the literature. Possible mechanisms of ibrutinib-mediated uveitis are explored.

Observations: Case 1 is a 60-year-old female who had been stable on 1 year of ibrutinib for chronic lymphocytic leukaemia.

Syphilitic punctate inner retinitis in immunocompetent gay men.

Purpose: To describe the features of an unusual syphilitic uveitis syndrome in a cluster of homosexual patients.

Design: Retrospective case series.

Participants: Five consecutive patients diagnosed with syphilitic retinitis in our Melbourne uveitis clinic over a period of 8 months.

Paraneoplastic syndromes associated with visual loss.

Purpose Of Review: The recent literature was reviewed to analyze the developments in the diagnosis, pathogenesis, and immunology of this group of paraneoplastic syndromes. Clinical features and pathologic findings are summarized.

Recent Findings: The mechanism of cell death in cancer-associated retinopathy appears to occur through apoptotic pathways.