Publications by authors named "Cecilia Gabriela Pascuan"
Article Synopsis
- Oxidative stress and neurotrophin levels are critical factors affecting brain function, particularly in stressed female BALB/c mice that exhibit poor learning performance, which can be reversed by glatiramer acetate (GA) treatment.
- The study involved chronic mild stress exposure for 9 weeks in mice, followed by GA injections, behavioral tests, and biochemical analyses of the hippocampus.
- Results showed that stressed mice had impaired learning linked to increased reactive oxygen species (ROS) and decreased nitric oxide (NO) production, but GA treatment restored normal ROS levels, improved nNOS activity, and enhanced cognitive performance.
It has been demonstrated that a short-duration stress (acute stress) may result in immunopreparatory or immunoenhancing physiological conditions. The aim of the present study was to investigate whether exposure to prenatal restraint stress (PRS) influences the impact of acute stress on the T-cell response in the adult life. We found that female mice exposed to PRS (PS mice) did not exhibit changes in the T-cell-dependent IgG antibody production with respect to prenatally non-stressed mice (no-PS mice).
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