Publications by authors named "Cecilia E Mareze da Costa"
The increasing incidence of diabetes mellitus is becoming a serious threat to human health in various parts of the world. Studies with dairy products have shown a potential beneficial effect against diabetes. This experiment evaluated the supplementation of milk naturally enriched with polyunsaturated fatty acids (PUFA) and polyphenols in rats with streptozotocin-induced diabetes.
View Article and Find Full Text PDFLiver mitochondrial function and redox status in an experimental model of non-alcoholic fatty liver disease induced by monosodium L-glutamate in rats.
Murilo de Oliveira Lazarin Emy Luiza Ishii-Iwamoto Nair Seiko Yamamoto Rodrigo Polimeni Constantin Rosângela Fernandes Garcia Cecília E Mareze da Costa
Exp Mol Pathol
December 2011
Article Synopsis
- The study aimed to explore the role of mitochondrial dysfunction in non-alcoholic fatty liver disease (NAFLD) using a rat model of obesity induced by monosodium L-glutamate (MSG).
- Results showed that liver mitochondria from these obese rats had increased fatty acid β-oxidation and oxidising capacity for succinate without impairing oxidative phosphorylation efficiency.
- The overall findings suggested that mitochondrial dysfunction does not contribute to liver fat accumulation in this model, and enhancements in specific enzyme activities may help defend against oxidative stress.