Publications by authors named "Cecilia Dell'Avalle"
Article Synopsis
- * In a study involving 93 patients, those who achieved ultrasound remission at week 12 had a significantly higher chance of long-term endoscopic remission (59%) compared to those without ultrasound remission (41%).
- * The findings suggest that achieving ultrasound remission early in treatment is important, indicating it should be considered a key treatment goal; further larger studies are needed for validation.
Article Synopsis
- The Milan ultrasound criteria (MUC) is a scoring system that evaluates endoscopic activity in ulcerative colitis (UC) and helps predict response to biologic treatments.
- In a study involving 49 UC patients starting biologic therapy, a MUC score of ≤ 6.2 at 12 weeks was found to be a strong predictor of endoscopic improvement, signifying successful treatment response.
- The study concludes that MUC is a reliable tool for monitoring treatment effectiveness and can be applied in both clinical trials and everyday medical practice.
Background: Endoscopic healing is an established treatment target for ulcerative colitis (UC). We have recently validated the Milan ultrasound criteria (MUC) to assess endoscopic activity in UC; a MUC score > 6.2 is a valid cut-off to discriminate endoscopic activity (Mayo endoscopic subscore > 1).
View Article and Find Full Text PDFIntroduction: Crohn's disease (CD) is a chronic, relapsing inflammatory bowel disease that can lead to significant organ damage and impaired quality of life. To date, a considerable proportion of patients does not respond to biologic compounds. It is, therefore, necessary to find alternative options with adequate efficacy and safety profiles in order to increase the chances of obtaining an enduring remission of disease.
View Article and Find Full Text PDFBackground: We developed a non-invasive bowel ultrasound score (BUSS) to assess disease activity in Crohn's disease (CD). BUSS >3.52 is an indicator of endoscopic activity (SES-CD>2).
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