Inter- and intra-observer reproducibility of quantitative renographic parameters of differential function and renal drainage in children.

Purpose: To evaluate inter- and intra-observer reproducibility of renographic quantitative parameters of input and output in children.

Methods: 100 children with unilateral or bilateral uropathy were selected, aiming to cover the entire range of ages, overall glomerular filtration rate (GFR), differential renal function (DRF) and quality of drainage. Renograms were acquired and processed according to the EANM guidelines, using a non-commercial software.

Late renal sequelae in intravenously treated complicated urinary tract infection.

Background: The treatment of complicated urinary tract infection in children is still a matter of debate. In our hospital, antimicrobial treatment is initiated intravenously, and the duration of this treatment is adapted according to the results of a Tc-99m dimercaptosuccinic acid (DMSA) scintigraphy.

Aim: This study was conducted to evaluate retrospectively the frequency and the importance of late renal sequelae when treating intravenously for 7 days those patients with an abnormal acute DMSA.

Is normalized residual activity a good marker of renal output efficiency?

Background: Output efficiency (OE) and normalized residual activity (NORA) are two parameters that allow quantifying the renal drainage at any moment of renographic acquisition. Although OE is theoretically more accurate than NORA in case of a decreased overall renal function, both parameters present some weaknesses.

Objectives: To compare both parameters and to evaluate whether the clinical information provided by both parameters is identical.

Can severely impaired cortical transit predict which children with pelvi-ureteric junction stenosis detected antenatally might benefit from pyeloplasty?

Introduction: Until recently, renogram, performed in children with pelvi-ureteric junction stenosis detected antenatally, has not been able to predict the probability of function improvement after surgery or the risk of function deterioration in case of conservative attitude. Recently, Schlotmann et al. have suggested that cortical transit might have this predictive role.

Normalized residual activity and output efficiency in case of early furosemide injection in children.

Objective: Values for output efficiency (OE) and normalized residual activity (NORA) in paediatric patients have been published previously. However, it is now a usual practice to inject furosemide at the beginning of a renogram acquisition (F0 procedure). The aim was to evaluate OE and NORA obtained on F0 renograms, in normal and abnormal paediatric kidneys.