Publications by authors named "Cecile Martaresche"
Article Synopsis
- The French Riviera had previously been considered free of Lyme Borreliosis (LB), but recent assessments show a notable prevalence of the disease in the Alpes-Maritimes region.
- Among 255 patients evaluated, 18% were confirmed cases of LB, with most experiencing ongoing infections after tick exposure in rural areas.
- Additionally, more than half of the patients were diagnosed with alternative conditions, including psychological and neurological issues, highlighting the importance of comprehensive diagnostic procedures.
Our main objective was to analyze the role of lipid rafts in the activation of Valpha-14(-) and Valpha-14(+) T hybridomas by dendritic cells. We showed that activation of Valpha-14(+) hybridomas by dendritic cells or other CD1d-expressing cells was altered by disruption of lipid rafts with the cholesterol chelator MbetaCD. However, CD1d presentation to autoreactive Valpha-14(-) anti-CD1d hybridomas which do not require the endocytic pathway was not altered.
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