Publications by authors named "Cecile Greze"

Background: Cancer treatments of the last decades improve the survival rate of children and adolescents. However, chemo- and radiotherapy result in gonadal damage, leading to acute ovarian failure and sterility. The preservation of fertility is now an integral part of care of children requiring gonadotoxic treatments.

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Article Synopsis
  • Many transgender individuals have high reproductive desires, but fertility preservation and sperm donation options in France were limited until recently due to restrictive Bioethics Law.
  • A national survey conducted at 28 reproductive technology centers revealed that a significant number of these centers provide services for fertility preservation, with 71.4% treating transgender patients.
  • Results indicated that transgender women are more likely to seek and achieve fertility preservation compared to transgender men, and a notable percentage of centers offer sperm donation services for couples including transgender men.
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Background: Numerous tests have been proposed to evaluate sperm DNA integrity. To assess the sperm chromatin dispersion (SCD) test in an andrology laboratory, twenty-five men attending Clermont-Ferrand (France) University Hospital's Center for Reproductive Medicine were recruited. Sperm DNA damage was measured in the same semen samples using the SCD test and the Terminal Uridine Nick-end Labeling by flow cytometry technique (TUNEL/FCM) after density gradient centrifugation.

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Objective: To evaluate the integrity of genomic imprinting in oocytes vitrified at the germinal vesicle (GV) stage and in vitro matured (IVM) after thawing.

Design: Clinical research and application.

Setting: University-based fertility center.

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