Publications by authors named "Cecile Farges"
Article Synopsis
- A retrospective study in Paris evaluated the effectiveness of neoadjuvant therapy with imatinib or pazopanib for patients with locally advanced dermatofibrosarcoma protuberans (DFSP) over a decade from 2007 to 2017.
- Among the 27 patients, treatment resulted in a 38.5% rate of complete or partial responses and an 85% disease-free rate after a median follow-up of about 65 months.
- Most patients underwent successful surgical removal of the tumor, although 85% experienced treatment-related adverse events, with few requiring significant treatment interruptions.
Recently, a novel group of CD34+ and S100+ spindle cell tumors with distinctive stromal and perivascular hyalinization showing recurrent gene fusions involving RAF1, BRAF, NTRK1/2/3, and RET has been identified. ALK rearrangements have been rarely reported in this group of tumors. We report a 24-year-old woman with a 1.
View Article and Find Full Text PDFAnecdotal cases of partial or complete responses have been reported after ipilimumab therapy for stage IV melanoma with brain metastasis treated earlier by surgery or radiosurgery. We report the first case of ipilimumab monotherapy resulting in durable complete remission of untreated, progressive brain metastases in a patient with stage IV melanoma. This case and earlier reports provide support for the further evaluation of ipilimumab in melanoma patients with brain metastasis.
View Article and Find Full Text PDFObjective: We describe a coaxial introducer provided with an additional blunt-tip stylet that allows safe access to difficult-to-reach lymph nodes in the chest, abdomen, and pelvis under CT control.
Conclusion: Once the thoracic, abdominal, or pelvic wall is crossed by the introducer fitted with the sharp-tip stylet, the blunt-tip stylet replaces the sharp stylet for further progression in the fat toward the target. The soft-tip stylet carries a smaller risk of inadvertent perforation displacing vital structures.