[Urine collection and pain in pediatric emergency departments].

In cases of suspected urinary infection when babies are admitted to emergency departments, a cyto-bacteriological urine test is necessary. Collection bags are associated with a high risk of "false positives" while catheterisation is an invasive technique. Nursing teams in the paediatric emergency departments of Limoges and Poissy general hospitals carried out a study to assess the benefits of both methods, the feasibility of catheterisation in children under 3 months and the pain this procedure causes.

Dose dependent expression of HDAC4 causes variable expressivity in a novel inherited case of brachydactyly mental retardation syndrome.

Histone deacetylase 4 (HDAC4) serves important roles in multiple human systems, including neurological, cardiac, and skeletal functions. Mutation or deletion of HDAC4 causes brachydactyly mental retardation syndrome (BDMR), a disorder that includes intellectual disability, behavioral abnormalities, autism spectrum disorder, and craniofacial and skeletal anomalies, including brachydactyly type E. We present a case of familial BDMR, including a parent with mild symptoms of the disorder and a child exhibiting a more severe phenotype.

Moving from bag to catheter for urine collection in non-toilet-trained children suspected of having urinary tract infection: a paired comparison of urine cultures.

Objective: To compare, in the same children, urine culture results from bag- versus catheter-obtained specimens with catheter culture as the reference.

Study Design: A total of 192 non-toilet-trained children <3 years of age from 2 emergency departments were recruited for this prospective cross-sectional study. All had positive urinalysis results from bag-obtained specimens that were systematically checked with a catheter-obtained specimen before treatment.