Publications by authors named "Cecile E du Toit"

Article Synopsis
  • The study focuses on the characteristics and treatment outcomes of acute promyelocytic leukemia (APL) patients in sub-Saharan Africa, specifically in Cape Town, South Africa.
  • A total of 69 patients were treated from 1998 to 2019, with 39% classified as high risk; early death rates were 7% at 7 days and 13% at 30 days.
  • Overall, the 3-year survival rate was 76.5%, which improved to 82.5% when excluding early deaths, indicating that despite challenges in the healthcare system, APL treatment outcomes in this region are comparable to those in developed countries.
View Article and Find Full Text PDF

A survey was carried out among the European Group for Blood and Marrow Transplantation (EBMT) centres to determine the incidence, risk factors, treatment and outcome of thrombotic thrombocytopenic purpura (TTP) following allogeneic haematopoietic stem cell transplantation. TTP was defined as the simultaneous occurrence of red cell fragmentation, laboratory findings of haemolysis, red cell transfusion requirement and de novo or persistent thrombocytopenia caused by consumption, in the absence of disseminated intravascular coagulation. Forty-five centres reported all patients (n = 406) transplanted between July and December 1996.

View Article and Find Full Text PDF