Publications by authors named "Cecile Duval"
Article Synopsis
- Social determinants of health (SDH) significantly influence child health outcomes, particularly regarding accessing care and the quality of care following injuries, but this relationship has not been systematically reviewed.
- The study will utilize Cochrane methodology to conduct a systematic review of various observational and experimental studies, analyzing factors such as race, socioeconomic status, and education that affect pediatric care after injuries.
- The findings aim to inform clinicians and policymakers to improve care systems and ensure equitable access to quality care for children and adolescents following traumatic events.
Article Synopsis
- The study reviews the effectiveness of neuromuscular blockers in treating Acute Respiratory Distress Syndrome (ARDS), which has a high mortality rate but no specific cure.
- Findings from six clinical trials involving 1,557 patients indicate that neuromuscular blockers are associated with lower mortality rates but do not significantly impact ventilator-free days or ICU length of stay.
- The comparison of light versus heavy sedation showed similar mortality outcomes, suggesting that a trial to further explore the benefits of lighter sedation could be beneficial.
Unlabelled: Venous thromboembolic events (VTE) are frequent complications in hospitalized patients and a leading cause of preventable death in hospital. Pharmacologic prophylaxis is a standard of care to prevent VTE in patients at risk, the additional value of intermittent pneumatic compression (IPC) is uncertain. We aimed to evaluate the efficacy of adding IPC to pharmacologic prophylaxis to prevent VTE in hospitalized adults.
View Article and Find Full Text PDFObjectives: Underuse of high-value clinical practices and overuse of low-value practices are major sources of inefficiencies in modern healthcare systems. To achieve value-based care, guidelines and recommendations should target both underuse and overuse and be supported by evidence from economic evaluations. We aimed to conduct a systematic review of the economic value of in-hospital clinical practices in acute injury care to advance knowledge on value-based care in this patient population.
View Article and Find Full Text PDFObjectives: Clinical services have allowed pharmacists to shift from product-oriented to patient-oriented services. However, the policy and social implications of clinical services in community pharmacies are not well described. The purpose of this scoping review was to identify these implications.
View Article and Find Full Text PDFThe complexation of the triptolide PG490 and its succinate derivative PG490-88Na with various cyclodextrins was studied using three complementary techniques: affinity capillary electrophoresis (ACE), isothermal titration calorimetry (ITC) and nuclear magnetic resonance (NMR). The apparent binding constants of the complexes formed between the drugs and 8 CDs (α-CD, β-CD, γ-CD, HP-α-CD, HP-β-CD, HP-γ-CD, CM-β-CD and amino-β-CD) were determined by ACE through linear Scott's plots. The apparent and averaged binding constants of the complexes formed between PG490-88 and β-CD, γ-CD, HP-α-CD, HP-β-CD or HP-γ-CD are contained in the narrow range 135-167 M(-1).
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