Prognostic value of uPA, PAI-1 and PAI-2 mRNA expression in primary breast cancer.

Background: The prognostic value of uPA, PAI-1 and PAI-2 mRNA expression was studied in a retrospective series of 130 primary breast cancer patients (median follow-up 8.1 years).

Materials And Methods: UPA, PAI-1 and PAI-2 mRNA were quantified by means of real-time quantitative RT-PCR.