Use of Anopheles salivary biomarker to assess seasonal variation of human exposure to bites in children living near rubber and oil palm cultivations in Côte d'Ivoire.

Environmental changes related to agricultural practices and activities can impact malaria transmission. In the objective to evaluate this impact on the human-vector contact, the level of human exposure to vector bites was assess by an immuno-epidemiological indicator based on the assessment of the human IgG antibody response to the gSG6-P1 salivary peptide, previously validated as a pertinent biomarker. Two cross-sectional surveys were carried out in the dry and rainy season in three villages with intensive agricultural plantations (N'Zikro with rubber cultivation, Ehania-V5 and Ehania-V1 with palm oil exploitation) and in a control village without plantations (Ayébo).

Evaluation of Human Exposure to Bites in Rubber and Palm Cultivations Using an Immunoepidemiological Biomarker.

Arbovirus infections, mainly transmitted by mosquito, are emerging in Africa. Efficient vector control requires an understanding of ecological factors which could impact on the risk of transmission, such as environmental changes linked to agricultural practices. The present study aims to assess the level of human exposure to mosquito bites in different agroecosystem area, using an immunological tool which quantifies human IgG antibody response to one salivary peptide.