Publications by authors named "Ceballos-Sanchez O"

Background: Lanthanide-based nanomaterials offer a promising alternative for cancer therapy because of their selectivity and effectiveness, which can be modified and predicted by leveraging the improved accuracy and enhanced decision-making of machine learning (ML) modeling.

Methods: In this study, erbium (Er) and ytterbium (Yb) were used to dope zinc oxide (ZnO) nanoparticles (NPs). Various characterization techniques and biological assays were employed to investigate the physicochemical and optical properties of the (Er, Yb)-doped ZnO NPs, revealing the influence of the lanthanide elements.

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The rise in antibiotic-resistant bacteria is a global health challenge. Due to their unique properties, metal oxide nanoparticles show promise in addressing this issue. However, optimizing these properties requires a deep understanding of complex interactions.

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The antioxidant capabilities of nanoparticles are contingent upon various factors, including their shape, size, and chemical composition. Herein, novel Nd-doped CeO nanoparticles were synthesized and the neodymium content was varied to investigate the synergistic impact on the antioxidant properties of CeO nanoparticles. Incorporating Nd induced changes in lattice parameters and significantly altered the morphology from nanoparticles to nanorods.

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This study used a sonochemical synthesis method to prepare (La, Sm)-doped ZnO nanoparticles (NPs). The effect of incorporating these lanthanide elements on the structural, optical, and morphological properties of ZnO-NPs was analyzed. The cytotoxicity and the reactive oxygen species (ROS) generation capacity of ZnO-NPs were evaluated against breast (MCF7) and colon (HT29) cancer cell lines.

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Immobilization of enzymes is one of the protein engineering methods used to improve their thermal and long-term stabilities. Immobilized pectinase has become an essential biocatalyst for optimization in the food processing industry. Herein, nanostructured magnetic nanoparticles were prepared in situ for use as supports to immobilize pectinase.

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Nanostructured ZnYbO (0.0 ≤ x ≤ 0.1) powders were prepared by the solution method using polyvinyl alcohol (PVA) and sucrose.

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Article Synopsis
  • Improving enzyme immobilization and facilitating direct electron transfer (DET) are crucial for enhancing the sensitivity of enzymatic electrochemical biosensors.
  • A novel method involves modifying halloysite nanotubes (HNTs) with silver nanoparticles (AgNPs) to create a hybrid nanocomposite that supports and connects redox enzymes effectively.
  • The resulting glucose oxidase (GOx) immobilized on the nanocomposite demonstrates significantly improved sensitivity in detecting glucose compared to electrodes without surface modifications, achieving up to 5.1 μA mM cm.
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