Publications by authors named "Cayuela L"

Background: Falls are a significant public health concern, particularly among older adults. This study aimed to analyse trends in fall-related mortality in Spain from 1999 to 2022, focusing on age and gender disparities.

Methods: Using a longitudinal ecological study, we analysed trends in fall mortality.

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Objective: To study melanoma incidence trends from 1990 to 2021 in Southern European countries-Portugal, Spain, Italy, Greece-and explore regional and age-period-cohort (A-P-C) patterns.

Methods: Data from the Global Burden of Disease Study 2021 were used to calculate age-standardized incidence rates (ASIRs). Joinpoint regression and age-period cohort (A-P-C) models were applied to identify trends and patterns.

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Objective: To analyse time trends in mortality due to cutaneous malignant melanoma (CMM) in Spain between 1980 and 2020, and to identify possible spatial clusters of provinces with an excess risk of CMM mortality during the period 2011-2020.

Methods: Joinpoint regression models were used to assess temporal trends in data from the Spanish National Institute of Statistics. Crude rates, standardized mortality ratio (SMR), smoothed relative risk (RR), and posterior probabilities (PP) of RR >1 during the period 2011-2020 were calculated.

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Objective: This study examines trends and disparities in kidney cancer (KC) mortality in Spain from 1983 to 2022, focusing on gender, birth cohort, and age influences.

Methods: Data from the Spanish National Institute of Statistics were analyzed using age-standardized mortality rates (ASMRs). Joinpoint regression identified temporal trends and annual percentage changes, while Age-Period-Cohort (A-P-C) analysis assessed the impacts of age, calendar period, and birth cohort on mortality.

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Introduction And Objectives: Infective endocarditis (IE) is a serious public health problem both in Spain and worldwide. This study aimed to analyze the trends in the incidence of IE in Spain from 1992 to 2021.

Methods: We used IE incidence data from the Global Health Data Exchange and population data from the Spanish National Statistics Institute to analyze changes in age-standardized incidence rates.

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Introduction: Lung cancer remains one of the leading causes of cancer death worldwide. This study examines lung cancer mortality trends in Andalusia, Spain, from 2003 to 2022, focusing on gender differences and the influence of age, period and cohort effects.

Material And Methods: This longitudinal ecological study analyzed lung cancer mortality data in Andalusia from 2003 to 2022, using age-period-cohort (A-P-C) and joinpoint regression models.

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Deforestation and forest degradation are key drivers of biodiversity loss and global environmental change. Ecosystem restoration is recognized as a global priority to counter these processes. Forest restoration efforts have commonly adopted a predominantly ecological approach, without including broader socioeconomic variables and the characteristics of the rural context.

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Objectives: This study examined the spatial patterns of systemic sclerosis mortality in Spain from 2003 to 2022, identifying provincial-level clusters and sex-specific differences to explore potential underlying factors.

Methods: Mortality and population data (2003-2022) were sourced from the National Institute of Statistics. Age-standardized mortality rates were calculated, and spatial patterns were analyzed using standardized mortality ratios and smoothed relative risks via the Besag, York, and Mollié model, with statistical inference performed using the Integrated Nested Laplace Approximation (INLA) technique.

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Aim: To explore trends in multiple sclerosis incidence rates in Spain between 1990 and 2019.

Methods: We use data from the Global Burden of Disease Study 2019 to calculate age-standardised incidence rates of multiple sclerosis and identify significant changes over time using the Joinpoint regression model. We also use the Age-Period-Cohort model to understand the separate influences of age, historical period, and birth cohort on these trends.

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Article Synopsis
  • This study examined psoriasis prevalence in Spain from 2018 to 2022, finding a significant increase in cases, particularly among older age groups.
  • The estimated prevalence reached 1.9% in 2022, with a total rise of 43.3%, indicating stronger increases in both men and women, with men showing slightly higher rates.
  • Results suggest factors like better awareness and diagnostics may contribute to this trend, highlighting the need for more research to understand the causes and inform public health strategies.
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Aim: This study aims to analyze trends in venous thromboembolism (VTE) mortality in the Spanish Autonomous Communities (ACs) from 1999 to 2022, with a focus on identifying regional disparities and informing targeted public health interventions.

Methods: Age-standardized mortality rates (ASMRs) were calculated using the European standard population as a reference. Joinpoint regression analysis was employed to identify significant changes in mortality trends, and geographical analysis was conducted using Bayesian inference to assess regional variations in mortality risk.

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  • The study analyzed melanoma mortality trends in Spain from 1999 to 2022, focusing on differences based on gender and age in various regions.
  • Results revealed significant regional variations in mortality rates, with higher rates for men in Eastern Spain and higher rates for women in Asturias, while trends showed fluctuating changes in specific areas over time.
  • The study emphasizes the need for ongoing monitoring and public health initiatives to address these disparities, particularly for older adults and men, to improve early detection and treatment access nationwide.
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  • - The study examines gastric cancer (GC) trends in Spain from 1990 to 2019, focusing on differences in incidence by sex and age.
  • - While the total number of GC cases slightly increased, the age-standardized incidence rate (ASIR) declined annually by 1.8% for both men and women, with men consistently having a higher burden of the disease.
  • - Notably, there was a significant decrease in ASIR among younger adults (<35 years), but a concerning rise was found in young men (25-34 years) between 2014-2019, indicating a need for further exploration of risk factors specific to this group.
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Article Synopsis
  • - From 1998 to 2022, MS hospitalization rates in Spain decreased by an annual average of -2.1%, with women showing a slightly higher decline (-2.3%) than men (-1.7%).
  • - Joinpoint analysis indicated non-parallel trends with three distinct periods of stabilization and decline, while age-standardized rates showed an overall drop, with rates peaking in younger age groups (25-29 for men and 30-34 for women).
  • - The research highlights that the risk of MS hospitalization is influenced by age, birth cohort, and sex, showing a significant decline despite an aging population, especially among cohorts born in the early 20th century.
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Mountains are paramount for exploring biodiversity patterns due to the mosaic of topographies and climates encompassed over short distances. Biodiversity research has traditionally focused on taxonomic diversity when investigating changes along elevational gradients, but other facets should be considered. For first time, we simultaneously assessed elevational trends in taxonomic, functional, and phylogenetic diversity of woody plants in Andean tropical montane forests and explored their underlying ecological and evolutionary causes.

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Non-melanoma skin cancer (NMSC) is the most -common skin cancer in Spain, yet national data on its incidence trends are limited. To analyse the trends in NMSC incidence in Spain from 1990 to 2019, examining variations by sex, age, period, and birth cohort. Data on NMSC incidence was sourced from the Global Health Data Exchange.

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Objective: Despite global declines in asthma mortality, regional variations and sex disparities persist. This study investigates asthma mortality trends in Spanish Autonomous Communities (ACs) from 1980 to 2022, analyzing data by sex.

Methods: Data on asthma deaths and population were obtained from the National Institute of Statistics for the study period.

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Aim: This study aimed to investigate the effects of age, period, and cohort on the incidence of psoriasis in Spain from 1990 through 2019 using the Global Burden of Disease (GBD) database and age-period-cohort (A-P-C) analysis.

Methods: We conducted an ecological trend study to analyze the incidence rates of psoriasis in Spain from 1990 through 2019. Joinpoint Regression Program, Version 5.

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Article Synopsis
  • This study analyzes lung cancer trends in Spain from 1990 to 2019, focusing on how age, period, and birth cohort affect incidence rates.
  • It found that nearly 738,000 lung cancer cases were diagnosed, with an overall annual increase of 1.7%, but a rise in women’s incidence rates (2.5% annually) and a decline in men's rates (-0.6%).
  • The results suggest a closing gender gap in lung cancer incidence due to decreasing smoking rates, highlighting the need for targeted prevention efforts for women and continued tobacco control measures.
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This response to an editorial discusses recent trends in gastric and pancreatic cancer mortality in Spain. The authors acknowledge the contrasting trajectories - a decrease in gastric cancer and an increase in pancreatic cancer - and attribute them to differing causes. Public health measures, particularly H.

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  • A study analyzed myelodysplastic neoplasm (MDS) mortality trends in Spain from 1999 to 2022, focusing on sex and regional differences.
  • The research revealed varying MDS mortality rates among men and women across different regions, with significant trends identified: initial decline until 2008, an increase until 2017, and a notable decrease thereafter.
  • Key findings included regional variations in mortality trends, with some areas like Andalusia experiencing increases, while others like Aragon saw declines; men consistently faced higher mortality risks than women, underscoring the need for localized healthcare strategies.
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Article Synopsis
  • Testicular cancer rates in Spain have doubled from 3.09 to 5.40 cases per 100,000 men between 1990 and 2019, indicating a 1.9% annual increase, while mortality rates have stabilized or decreased in younger groups.
  • The study utilized the Global Burden of Disease database and the Age-Period-Cohort model to analyze trends and found a significant rise in incidence linked to successive generations born after 1935, contrasting with a decline in mortality among those born since the 1960s.
  • Despite the decrease in mortality being a positive sign, the rising incidence trends highlight a need for further research to uncover the causes and develop effective prevention strategies for testicular cancer.
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Objective: This study aimed to assess the influence of age, period, and cohort (A-P-C) factors on kidney cancer (KC) incidence trends in Spain from 1990 to 2019.

Methods: Employing data from the Global Burden of Disease Study 2019, we employed joinpoint analysis to determine long-term patterns and A-P-C modelling to quantify net drift, local drift, longitudinal age curves, and rate ratios (RRs) of period and cohort effects.

Results: Over the period 1990-2019, an estimated 142,811 cases of KC were diagnosed in Spain.

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Aim: This study aims to elucidate the factors driving melanoma incidence trends in Spain by analyzing the GBD-2019 dataset (1990-2019) and investigating the age-specific, birth cohort, and period effects on incidence rates.

Materials And Methods: This study analyzed melanoma incidence trends in Spain from 1990 to 2019 using an ecological design. Data were sourced from the Global Burden of Disease Study 2019 and Spain's National Statistics Institute.

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Aim: This study aimed to evaluate how age, period, and cohort (A-P-C) impact colorectal cancer (CRC) incidence in Spain from 1990 to 2019.

Method: Using data from the Global Burden of Disease Study 2019, we used joinpoint analysis to identify long-term trends and A-P-C modelling to quantify net drift, local drift, longitudinal age curves, and rate ratios (RRs) of period and cohort effects.

Results: CRC incidence increased steadily in Spain from 1990 to 2019, with a more significant rise in males than in females.

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