The Core outcome Clubfoot (CoCo) study: relapse, with poorer clinical and quality of life outcomes, affects 37% of idiopathic clubfoot patients.

Aims: There is a lack of high-quality research investigating outcomes of Ponseti-treated idiopathic clubfeet and correlation with relapse. This study assessed clinical and quality of life (QoL) outcomes using a standardized core outcome set (COS), comparing children with and without relapse.

Methods: A total of 11 international centres participated in this institutional review board-approved observational study.

Mothering While Sick: Poor Maternal Health and the Educational Attainment of Young Adults.

At a time when educational attainment in young adulthood forecasts long-term trajectories of economic mobility, better health, and stable partnership, there is more pressure on mothers to provide labor and support to advance their children's interests in the K-12 system. As a result, poor health among mothers when children are growing up may interfere with how far they progress educationally. Applying life course theory to the National Longitudinal Study of Adolescent to Adult Health to investigate this possibility, we found that young adults were less likely to graduate from college when raised by mothers in poor health, especially when those mothers had a college degree themselves.

A 'Hub and Spoke' Shared Care initiative for CTEV Ponseti service.

Aims: The Ponseti method is the gold standard treatment for congenital talipes equinovarus (CTEV), with the British Consensus Statement providing a benchmark for standard of care. Meeting these standards and providing expert care while maintaining geographical accessibility can pose a service delivery challenge. A novel 'Hub and Spoke' Shared Care model was initiated to deliver Ponseti treatment for CTEV, while addressing standard of care and resource allocation.

Tackling antimicrobial resistance: developing and implementing antimicrobial stewardship interventions in four African commonwealth countries through a health partnership model.

In recent years, health partnerships have shared infection prevention and control innovations between United Kingdom hospitals and Low-Middle-Income Countries. However, none had focused on antimicrobial stewardship (AMS), a core component of tackling antimicrobial resistance (AMR). This paper documents an effective approach to developing a program to increase AMS capacity in four African countries: Ghana, Tanzania, Uganda, and Zambia as part of the Commonwealth Partnerships for Antimicrobial Stewardship (CwPAMS) program.

NYS Nonprofit Hospital Assessment and Response to Environmental Pollution as Community Health Need: Prevalence in Community Benefit Practices.

Context: Given the impact of environmental pollution on health and health inequity, there may be substantial value in integrating assessment and response to pollution into nonprofit hospital community benefit processes. Such hospital engagement has not yet been studied.

Objectives: We take a preliminary step of inquiry in investigating if nonprofit hospitals in New York State (NYS) assess, identify, or respond to environmental pollution as part of community benefit processes.

Family Formation History and the Psychological Well-Being of Women from Diverse Racial-Ethnic Groups.

Studying disparities in psychological well-being across diverse groups of women can illuminate the racialized health risks of gendered family life. Integrating life course and demand-reward perspectives, this study applied sequencing techniques to the National Longitudinal Study of Youth: 1979 to reveal seven trajectories of partnership and parenthood through women's 20s and 30s, including several in which parenthood followed partnership at different ages and with varying numbers of children and others characterized by nonmarital fertility or eschewing such roles altogether. These sequences differentiated positive and negative dimensions of women's well-being in their 50s.

A Multi-Centre, Single-Arm Clinical Study to Confirm Safety and Performance of PuraStat®, for the Management of Bleeding in Elective Carotid Artery Surgery.

Anastomotic bleeding in vascular surgery can be difficult to control. Patients, in particular those undergoing carotid surgery, have often been started on treatment with dual antiplatelet agents and receive systemic heparinization intraoperatively. The use of local hemostatic agents as an adjunct to conventional methods is widely reported.

Development and Implementation of an Antimicrobial Stewardship Checklist in Sub-Saharan Africa: A Co-Creation Consensus Approach.

Antimicrobial stewardship (AMS) initiatives promote the responsible use of antimicrobials in healthcare settings as a key measure to curb the global threat of antimicrobial resistance (AMR). Defining the core elements of AMS is essential for developing and evaluating comprehensive AMS programmes. This project used co-creation and Delphi consensus procedures to adapt and extend the existing published international AMS checklist.

Development of and User Feedback on a Board and Online Game to Educate on Antimicrobial Resistance and Stewardship.

Antimicrobial resistance (AMR), particularly antibiotic resistance, is one of the most challenging global health threats of our time. Tackling AMR requires a multidisciplinary approach. Whether a clinical team member is a cleaner, nurse, doctor, pharmacist, or other type of health worker, their contribution towards keeping patients safe from infection is crucial to saving lives.

Sociotherapy in the Time of COVID-19: A Critical Position Paper on the Importance of Sociology.

This paper contends that sociotherapy, a sociologically informed approach to therapy, is a viable alternative to the diagnostic model recognized by the College of Registered Psychotherapists in Ontario (CRPO). The Psychotherapy Act (2007) along with the Regulated Health Professions Act (1991) gives the CRPO authorization to regulate the practice of psychotherapy and to control titles affiliated with the act of psychotherapy. I offer a discussion of sociotherapy and socioanalysis as clinical alternatives to the conservative and normalizing approaches endorsed by the College.

Maternal Education and Early Childhood Education across Affluent English-Speaking Countries.

Women who attain more education tend to have children with more educational opportunities, a transmission of educational advantages across generations that is embedded in the larger structures of families' societies. Investigating such country-level variation with a life course model, this study estimated associations of mothers' educational attainment with their young children's enrollment in early childhood education and engagement in cognitively stimulating activities in a pooled sample of 36,400 children ( = 17,900 girls, 18,500 boys) drawn from nationally representative datasets from Australia, Ireland, United Kingdom, and United States. Results showed that having a mother with a college degree generally differentiated young children on these two outcomes more in the United States, potentially reflecting processes related to strong relative advantage (i.

A Diversity of Intrinsic Timescales Underlie Neural Computations.

Neural processing occurs across a range of temporal scales. To facilitate this, the brain uses fast-changing representations reflecting momentary sensory input alongside more temporally extended representations, which integrate across both short and long temporal windows. The temporal flexibility of these representations allows animals to behave adaptively.

Family Structure and Secondary Exposure to Violence in the Context of Varying Neighborhood Risks and Resources.

Secondary exposure to violence in the community is a prevalent developmental risk with implications for youths' short- and long-term socioemotional functioning. This study used longitudinal, multilevel data from the Project on Human Development in Chicago Neighborhoods to consider how family structure, including parental instability, is associated with youths' secondary exposure to violence across diverse neighborhood contexts. Results showed that both living in a stable single-parent household and experiencing parental instability were associated with greater secondary exposure to violence compared with living in a stable two-parent household.

A circuit mechanism for decision-making biases and NMDA receptor hypofunction.

Decision-making biases can be features of normal behaviour, or deficits underlying neuropsychiatric symptoms. We used behavioural psychophysics, spiking-circuit modelling and pharmacological manipulations to explore decision-making biases during evidence integration. Monkeys showed a pro-variance bias (PVB): a preference to choose options with more variable evidence.

Family Instability in the Lives of American Children.

Scholars have long looked to family composition to understand child well-being. Family instability, or the experience of repeated changes in parents' union status during childhood, represents a recent advance in this field that takes into account the dynamic nature of contemporary family organization and considers its implications for children's adjustment and development. We review some of the structural and cultural factors that have contributed to rising levels of family instability and highlight the emergence of national data to measure it.

Postcraniectomy pain: comparison between 2 incisions for the retrosigmoid approach. Prospective randomized study.

Background: Suboccipital lateral approach is a common practice in neurosurgery to expose the region of the cerebellopontine angle. Postcraniectomy headache (PCH) is one of the most frequent complications that diminish the quality of life of patients.

Objective: To compare postcraniectomy pain in patients operated on for vestibular neurinomas by a suboccipital lateral approach by 2 different incisions.

Wigner Near-Threshold Effects in the Photoelectron Angular Distribution of NO.

High-resolution velocity map imaged photoelectron spectra of the nitrite anion NO are measured over a range of photodetachment wavelengths between 355 and 550 nm, resolving the vibrational and rotational structure of the NO() + ← NO() + transition. A full rotational band model is constructed to define the spectroscopic constants of both the neutral and the lesser studied anion ground states. The corresponding photoelectron angular distributions are characterized by a large positive anisotropy parameter, with β ≈ 1.

Family structure patterns from childhood through adolescence and the timing of cohabitation among diverse groups of young adult women and men.

Family structure changes experienced by children are likely to shape their transitions into young adulthood, including the formation of their own romantic relationships. This study examined links between children's family structure trajectories from childhood through adolescence and their timing of entry into cohabitation as young adults, a transition with implications for future relationship instability through adulthood. Repeated measures latent class analysis identified configurations of family structures and family structure changes from birth through age 15 among 10,706 young people in the National Longitudinal Survey of Youth, 1979 Children and Young Adults.

Visual fixation patterns during economic choice reflect covert valuation processes that emerge with learning.

Visual fixations play a vital role in decision making. Recent studies have demonstrated that the longer subjects fixate an option, the more likely they are to choose it. However, the role of evaluating stimuli covertly (i.

Estimating Children's Household Instability Between Birth and Age 18 Using Longitudinal Household Roster Data.

Previous descriptions of the composition and stability of children's households have focused on the presence of parents and the stability of mothers' marital and cohabiting relationships. We use data available in the 2008 Survey of Income and Program Participation to expand the description of children's household composition and stability. We find that one in five children lives with nonnuclear household members.

Mothers' Partnerships, Men in the Home, and Adolescents' Secondary Exposure to Violence.

Family instability means that many U.S. youth spend time without biological fathers and with other men.