Conservation risks for paper collections induced by the microclimate in the repository of the Alessandrina Library in Rome (Italy).

The Alessandrina Library was founded in 1667 by pope Alexander VII Chigi and is nowadays housed in the Campus of Sapienza University of Rome (Italy). Within its Ancient (mostly made of rag paper) and Modern (mostly made of contemporary paper) collections, it includes more than one million books produced from the XVI to the XXI century. In 2019, six thermo-hygrometers were deployed in its multi-storey repository to monitor temperature (T) and relative humidity (RH).

Long-term treatment response to continuous cycling course in bipolar disorders: A meta-analysis.

Objective: About 30% of patients with bipolar disorders (BD) exhibit a continuous cycling course (CCC). These patients significantly differ from those with non-continuous cycling course (NCCC) on clinical presentation and have a poorer short-term response to antidepressant treatment. Our aim is to conduct a meta-analysis of the studies comparing long-term treatment response in CCC and NCCC bipolar patients.

Continuous circular cycling as a predictor of treatment response in bipolar disorders: a comprehensive review of the current literature.

Evidence from the literature suggests that, on average, 27% of patients with a bipolar disorder (BD) experience a continuous cycling course (CCC) and that this subgroup differs significantly from patients with a noncontinuous cycling course (N-CCC) with respect to sociodemographic characteristics and clinical presentation. The aim of the present paper is to review the studies that evaluated short- and long-term treatment responses in BD patients with CCC. The retrieved studies indicate that CCC is a significant predictor of poor response to long-term treatment with lithium (the odds of a response in the CCC group were 57% less than in the N-CCC group; p<0.

[Pharmacotherapy plus psychotherapy in patients with mood disorder and Axis II codiagnosis. A review].

Aim: The main aim of this paper is to review data on the efficacy of combined therapy in patients with mood disorder and axis II codiagnosis. The secondary aim is to assess the impact of personality disorders, psychotherapies, and combination therapy approaches on the treatment outcome.

Materials And Methods: We searched the Medline database using the following syntax: "major depressive disorder", "bipolar depression", "personality disorder", "comorbidity", "epidemiology", "combined therapy", "sequential therapy".

Treating bipolar depression - antidepressants and alternatives: a critical review of the literature.

Objective: Although depressive symptoms are preponderant in the course of bipolar (BP) disorders, the treatment of BP depression remains a controversial issue with different clinical approaches available. This review addresses the issues of whether antidepressants (ADs) are effective in treating acute and long-term BP depression, risks linked to ADs and what alternatives to ADs are available.

Methods: We searched the MEDLINE databases using the following syntax: [bipolar depression AND unipolar depression AND (antidepressants OR anticonvulsants OR lithium OR antipsychotics OR dopamine-agonists OR psychoeducation OR psychotherapy OR electroconvulsive therapy OR transcranial magnetic stimulation)].

[Insulin resistance and metabolic profile in lean and overweight/obese polycystic ovary syndrome patients].

Objective: To evaluate insulin sensitivity and the metabolic features in normal weight and overweight/obese patients with PCOS.

Subjects And Methods: Forty-nine (49) patients from 18 to 45 years were retrospectively evaluated and divided into 2 groups, according to the body mass index (BMI): group 1 (18.5-24.

Patterns of adaptation and school performance: a pilot study.

A group of 34 pupils from two school classes (Class 8, M = 13.1 yr., SD=0.

[Presence of asbestos in naval vessels: study of airborne fiber concentrations on Italian railways ferry boats].

Asbestos has been widely used on ships as an insulating material due to its fire-resistant and sound-absorbent properties. It was therefore deemed appropriate to measure the concentrations of airborne asbestos fibres on two ferries in regular service on the Civitavecchia-Golfo Aranci route. Decontamination work had been carried out on these vessels in order to remove, as far as possible, or to confine asbestos.