An animal study on the bone behaviour of Ca-P-coated implants: influence of implant location.

Four different implant materials were installed into the mandibular corner of goats to investigate the trabecular bone response in a mainly unloaded model. The implants were installed using a standardized technique and were left in situ for 12 weeks. One goat had to be sacrificed after surgery because of a broken rib; the other animals healed uneventfully.

The relationship of some histologic parameters, radiographic evaluations, and Periotest measurements of oral implants: an experimental animal study.

The objective of this study was to analyze the efficacy and correlation between clinical and histologic parameters used to evaluate oral implants. After extraction of the premolars and a healing time of 4 months in 16 Dutch goats, four Brånemark implants were placed in the maxillary left and right premolar regions. After a healing time of 6 months, followed by another 4 months with the permucosal abutments, the goats were sacrificed and the jaws were block-resected.

A histological and histomorphometrical evaluation of the application of screw-designed calciumphosphate (Ca-P)-coated implants in the cancellous maxillary bone of the goat.

Various studies already have shown that the occurrence of oral implant failure is higher in the maxilla than in the mandible. To learn whether Ca-P coatings can improve the success rate of oral implants in the maxilla, three different plasma-sprayed, Ca-P-coated, self-tapping Brånemark implants were inserted in the trabecular bone of the maxilla. Before the insertion of the implants, the two first upper premolars of 16 goats were bilaterally extracted.

Assessment of bone surrounding implants in goats: ex vivo measurements by dual X-ray absorptiometry.

The aim of the present study is to determine the possibility of measuring the bone mineral density (BMD) around implants by dual energy X-ray absorptiometry (DEXA). Therefore, the trabecular BMD was measured close to 127-600 microns and at a distance from various uncoated and Ca-P-coated implants inserted into the femoral condyle of goals. The implants were left in situ for 12 weeks.

The effect of Ca-P plasma-sprayed coatings on the initial bone healing of oral implants: an experimental study in the goat.

The response of bone of low density to uncoated, fluorapatite (FA), hydroxyapatite (HA), and hydroxyapatite heat treated (HAHT) plasma-sprayed coated implants was investigated 3 and 6 months after installation. Forty-eight threaded implants of commercially pure titanium were inserted into the maxilla of twelve goats according to a split-plot design. One goat died shortly after installation of the implants, five goats were sacrificed 3 months after installation, and the other six goats 6 months after installation.

Evaluation of Ca-P coatings in animal experiments: importance of study design.

During the last decennium the research on oral implants has increased considerably. A lot of different implant materials and types have been tested, but differences in study design and evaluation criteria make comparison of the results difficult. The purpose of this paper is to discuss surgical, statistical, and histological methods for testing and evaluating the biocompatibility of oral implants.

Effect of calcium phosphate (Ca-P) coatings on trabecular bone response: a histological study.

The trabecular bone response to noncoated and fluorapatite (FA), hydroxyapatite (HA), and hydroxyapatite heat-treated (HAHT) plasma-sprayed coated implants was investigated in a goat animal model. Forty-eight cylindrical implants were inserted into the trabecular bone of the lateral and medial femoral condyles of twelve goats according to a split plot design. After an implantation period of twelve weeks, the bone-implant interface was evaluated histologically.