Does aPDT reduce bacterial load in endodontic infected teeth? A systematic review and meta-analysis.

This systematic review investigated whether antimicrobial photodynamic therapy (aPDT) after chemomechanical root canal disinfection (CD) yields a greater microbial load reduction than only CD. An electronic literature search was conducted on four databases up to November 2022, with no language or publication date restrictions. Randomized and non-randomized clinical trials were included if participants had a primary endodontic infection in permanent teeth, and if microbial loads before and after using aPDT were compared.

Cross Talk between Apical Periodontitis and Metabolic Disorders: Experimental Evidence on the Role of Intestinal Adipokines and Akkermansia muciniphila.

Introduction: Infection and dysbiosis present a close relationship with metabolic diseases although the influence of apical periodontitis (AP) in this context needs further investigation. This study evaluated the influence of AP in a rat model of metabolic syndrome induced by 10% fructose supplementation.

Methods: Male Wistar rats were used.

In vitro antibacterial activity of a silicone-based endodontic sealer and two conventional sealers.

The aim of this study was to evaluate whether the modification in the silver component is capable of providing GuttaFlow 2 with antibacterial activity against Enterococcus faecalis compared with epoxy resin-based (AH Plus) and zinc oxide and eugenol-based (Endofill) sealers. The antibacterial activity was evaluated using a reference strain of E. faecalis (ATCC 29212).

Tissue reactions to a new mineral trioxide aggregate-containing endodontic sealer.

Introduction: The purpose of this study was to analyze the connective tissue reactions to MTA Fillapex (Ângelus Indústria de Produtos Odontlógicos Ltda, Londrina, Brazil) compared with a zinc oxide-based sealer (EndoFill; Dentsply Indústria e Comérico Ltda, Petrópolis, Brazil) and an epoxy resin-based material (AH Plus; Dentsply DeTrey GmbH, Konstanz, Germany) in Wistar rats.

Methods: Polyethylene tubes containing the test materials and empty polyethylene tubes (control) were implanted in the subcutaneous tissue of 12 rats. Empty tubes were used as a negative control.