Publications by authors named "Catia Iracema Morais"
Article Synopsis
- CD4+ T cells are crucial for the immune system, but their exact function is not fully understood, particularly the role of the CD4 protein itself.
- Researchers studied seven patients with a rare genetic condition causing CD4 deficiency, leading to various infections, and found that these individuals lacked CD4+ T cells but had alternative T cell populations that could still mount immune responses.
- While the patients showed compensatory immune responses against many pathogens, CD4 remains essential for protection against specific infections like human papillomavirus and Whipple's disease.
Background And Aims: Primary biliary cholangitis (PBC) is an immune-mediated liver disease. The immunological profile seems to relate to clinical prognosis. This study aims to determine the role of autoantibodies in the course of liver disease and in the response to ursodeoxycholic acid.
View Article and Find Full Text PDFBackground: Automated, technically simple analytical methods offering objective results are highly valued in clinical laboratories. Kappa free light chains (KFLC) in cerebrospinal fluid (CSF) are promising multiple sclerosis (MS) biomarkers, particularly kappa (K) index.
Methods: KFLC were determined in CSF and serum samples of patients diagnosed with MS, clinically/radiologically isolated syndrome (N, 39), and controls (N, 152; inflammatory and non-inflammatory neurological disorders).
The case highlights the importance of actively obtaining informative samples at an early stage and of prompt initiation of combination therapy with antifungal drugs.
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