A randomized controlled trial of a structured exercise intervention after the completion of acute cancer treatment in adolescents and young adults.

Background: Cancer treatments are frequently associated with impaired physical fitness, quality of life (QOL), and fatigue, often persisting into survivorship.  Studies in older adults with cancer have demonstrated benefits from exercise; however, this has not been rigorously investigated in adolescents and young adults (AYA). The aim of this study was to determine whether a structured 10-week exercise intervention was associated with improved cardiorespiratory fitness (VO ), fatigue, and QOL in AYA who have recently completed cancer treatment.