Whereas environmental challenges during gestation have been repeatedly shown to alter offspring brain architecture and behavior, exploration examining the consequences of paternal preconception experience on offspring outcome is limited. The goal of this study was to examine the effects of preconception paternal stress (PPS) on cerebral plasticity and behavior in the offspring. Several behavioral assays were performed on offspring between postnatal days 33 (P33) and 101 (P101).
View Article and Find Full Text PDFBackground: The most common cause of surgical readmission after breast implant surgery remains infection. Six causative organisms are principally involved: Staphylococcus epidermidis and S. aureus, Escherichia, Pseudomonas, Propionibacterium, and Corynebacterium.
View Article and Find Full Text PDFObjective: Patients with treatment-resistant schizophrenia commonly receive nonrecommended drug regimens, including antipsychotic polypharmacy, sometimes in lieu of clozapine. This analysis compared utilization and cost outcomes for cohorts of Medicaid beneficiaries treated with clozapine monotherapy and with antipsychotic polypharmacy.
Methods: Data were from the Medicaid MarketScan database.
Tactile stimulation (TS) applied to adult rats after cortical injury (medial frontal cortex aspiration or sensorimotor pial stripping stroke model) has been previously shown to ameliorate behavioral impairments and to improve morphological parameters like dendritic length of prefrontal cortical neurons (Gibb et al., 2010). The purpose of this study was to examine the effect of TS on healthy and hemiparkinsonian adult rats.
View Article and Find Full Text PDFExposure of the developing brain to a wide variety of drugs of abuse (e.g., stimulants, opioids, ethanol, etc.
View Article and Find Full Text PDFPurpose: The goal of this study was to determine the causes of increased post-arthroscopy surgical site infections (SSIs) and to define risk factors for infection.
Type Of Study: Outbreak investigation and case control study at a university-affiliated community hospital from 1994 to 1996, with surveillance through 1999.
Methods: Demographic, clinical, and microbiological data were collected on 27 post-arthroscopy SSIs from 1994 through 1999.
Infect Control Hosp Epidemiol
January 2003
Objective: To characterize risk factors for surgical-site infection after spinal surgery.
Design: A case-control study.
Setting: A 113-bed community hospital.