Publications by authors named "Cathy C Cantilena"
Article Synopsis
- Hematopoietic stem cell (HPC) donors treated with granulocyte-colony-stimulating factor (G-CSF) can experience adverse reactions, including elevated levels of serum proBNP, a marker associated with heart failure.
- A study analyzed 18 healthy donors who received G-CSF and found that 86.7% showed increased proBNP levels post-treatment, with some exceeding the normal range.
- The findings suggest that while elevated proBNP is common among these donors, it isn't linked to heart dysfunction, and further research is needed to identify risk factors for significant proBNP increases.
Background: Characterizing the kinetics of the antibody response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is of critical importance to developing strategies that may mitigate the public health burden of coronavirus disease 2019 (COVID-19). We conducted a prospective, longitudinal analysis of COVID-19 convalescent plasma donors at multiple time points over an 11-month period to determine how circulating antibody levels change over time following natural infection.
Methods: From April 2020 to February 2021, we enrolled 228 donors.
Background: Characterizing the kinetics of the antibody response to SARS□CoV□2 is of critical importance to developing strategies that may mitigate the public health burden of COVID-19. We sought to determine how circulating antibody levels change over time following natural infection.
Methods/materials: We conducted a prospective, longitudinal analysis of COVID-19 convalescent plasma (CCP) donors at multiple time points over a 9-month period.
Background: Recombinant immunoblot assay (RIBA) is used to determine the specificity of antibody to hepatitis C virus (anti-HCV). The RIBA result is recorded as positive, negative, or indeterminate. The interpretation and significance of RIBA-indeterminate reactions are unclear.
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