Publications by authors named "Catherine Tachdjian"
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Synopsis of recent research by authors named "Catherine Tachdjian"
- Catherine Tachdjian's research centers on the functional mechanisms of taste receptors, particularly the sweet and bitter taste receptors, emphasizing the discovery of biased ligands and their therapeutic potential as modulators and antagonists.
- Recent studies highlight the development of S6821 and S7958 as potent TAS2R8 antagonists to mitigate bitterness in substances that activate this receptor, which could enhance the palatability of various pharmaceutical compounds.
- Tachdjian's ongoing work also involves evaluating novel flavor compounds for safety and exploring allosteric modulation strategies to improve sweetness perception without adding calories, showcasing a commitment to addressing dietary health challenges posed by sugar consumption.